ISSN:
1432-0533
Keywords:
Tuberous Sclerosis
;
Electron Microscopy
;
Cerebral Biopsy
;
Astrocytes
;
Cerebral Tumor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The electron microscopic study of a cortical biopsy from a child presenting a Tuberous Sclerosis shows the importance of the astrocytic gliosis, the existence of abnormal cells of which two types can be recognized, and the presence of giant cells. All these cells are remarkable by the abundance of the ergastoplasm, the development of the Golgi apparatus, and the presence of membrane bound dense bodies. These cells are undoubtedly of astrocytic origin and appear very similar to the cells observed in a tumour of the caudate nucleus of another child affected by the same disease. These morphological data lead to believe that the cerebral abnormalities of the Tuberous Sclerosis essentially concern the astrocytes. The main characteristic of this astrocytic lesion would be its blastomatous potentiality.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00691754
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