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  • Anaesthesia  (1)
  • IPPB (Intermittent positive pressure breathing)  (1)
  • 1
    ISSN: 1433-8580
    Keywords: Rat ; Halothane ; Anaesthesia ; Regional blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The haemodynamic effects of halothane-N2O/O2 anaesthesia with controlled ventilation were studied in rats, using the microsphere method. Mean arterial blood pressure was significantly reduced but only minor effects on cardiac output (CO), heart rate, and systemic vascular resistance were seen. During anaesthesia, there were significantly increased fractions of CO delivered to brain, lungs, small intestine and liver (hepatic artery), while the fractions to spleen, stomach and carcass were decreased. Fractional distribution and regional blood flow to heart, kidneys, adrenals and preportal area remained unchanged. When anaesthesia was prolonged from 60 to 90 min, no further changes in central or regional haemodynamics were seen. Considering the minor effects on central haemodynamics and the abscense of changes in central and regional haemodynamics at 60 and 90 min, this anaesthesia model should be useful in experimental research.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 1 (1975), S. 129-136 
    ISSN: 1432-1238
    Keywords: Microembolism ; arthroplasty ; lung function ; Xe133 radiospirometry ; IPPB (Intermittent positive pressure breathing) ; epidural anesthesia ; pulmonary blood volume
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With a Xenon133 radiospirometric technique the regional lung function was evaluated before and after prosthetic hip arthroplasty performed in the lateral decubitus position with either respirator-controlled neuroleptic anesthesia or epidural anesthesia with spontaneous breathing. Regional lung function measured in a supine position 1, 20 and 72-96 hours postoperatively revealed a reduction of the perfusion, ventilation and volume of ventilated alveoli on the dependant lung. The reduction was most pronounced immediately postoperatively, especially following respirator-controlled anesthesia. There was also an increase of pulmonary blood volume and a decrease of total lung volume in this group. The changes of lung function are probably caused by congestive atelectasis, secondary to impaired ventilation of the dependent lung. Peroperatively induced microembolism might have potentiated the effect.
    Type of Medium: Electronic Resource
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