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  • Analytical Chemistry and Spectroscopy  (1)
  • Cardiac muscle  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Propagation of excitation-contraction coupling into ventricular myocytes (1994)
    Springer
    Pflügers Archiv 428 (1994), S. 415-417 
    Details
    ISSN: 1432-2013
    Keywords: Heart ; Cardiac muscle ; Contraction ; E-C coupling ; Calcium channels ; Ryanodine receptors ; Intracellular calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper examines the [Ca2+]i transient in isolated rat heart cells using a laser scanning confocal microscope and the calcium indicator fluo-3. We find that the depolarization-evoked [Ca2+]i transient is activated synchronously near the surface and in the middle of the heart cell with similar kinetics of activation. The time of rise of the transient did not depend on whether the sarcoplasmic reticulum (SR) Ca-release was abolished (by thapsigargin and ryanodine). The synchrony of activation and the similarity of levels of [Ca2+]i at the peripheral and deeper myoplasm (regardless of the availability of SR Ca-release) shows that sarcolemmal Ca channels and SR Ca-release channels are distributed throughout the rat heart cell and that the propagation of the action potential into the interior of the cell is rapid. In addition, the activation of calcium release from the SR by CICR is rapid (≪2 ms) when compared to the time-course of calcium influx via the sarcolemmal Ca channel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00724526
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Temperature dependence of the carbon-13 chemical shifts of paraffinic hydrocarbons (1978)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 11 (1978), S. 457-460 
    Details
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A study of several linear and branched alkanes indicates that the temperature dependence of 13C chemical shifts is a complex phenomenon in which several non-additive effects may be operative. The chemical shift temperature coefficients dδ/dT do, however, reveal some systematic trends which could be helpful in the assignments of 13C resonances. An empirical equation is proposed (akin to that of Grant and Paul for 13C chemical shifts) which accurately correlates all the data obtained near ambient temperatures.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1270110908
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    Paper (German National Licenses)
    Fulltext
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