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Attenuation of endothelium-dependent relaxation in mesenteric artery during noise-induced hypertension (1993)

Wu, C. C. ; Chen, S. J. ; Yen, M. H.

Springer

Journal of biomedical science 1 (1993), S. 49-53

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ISSN: 1423-0127

Keywords: Noise ; Endothelium ; A23187 ; Acetylcholine ; Nitroglycerin

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract The present study was designed to determine whether there is a causal relationship between noise-induced hypertension and changes of endothelial function. Rats were exposed to noise stress (100 dB, 1 kHz, 4 h/day, 6 days/week) for 1–4 weeks. The systolic blood pressure was significantly increased after rats were exposed to noise stress for 3 weeks. The relaxant responses of isolated mesenteric arterial rings to endothelium-dependent vasodilators (A23187 and acetylcholine) in noise-treated rats were significantly less than those in control rats. This difference in response to acetylcholine still existed in the presence of methylene blue or Nω-nitro-L-arginine. On the other hand, the responses to the endothelium-independent vasodilator nitroglycerin were not affected in rats exposed to noise stress. The attenuation to endothelium-dependent vasodilators during noise stress may result in increasing peripheral vascular resistance and thus elevate blood pressure. This indicates that noise-induced hypertension may be partly due to the alterations of endothelial activity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02258339

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Molecular reorientation and vibrational relaxation in dibromomethane (1984)

Chen, S. J. H. ; Schwartz, M.

Chichester [u.a.] : Wiley-Blackwell

Journal of Raman Spectroscopy 15 (1984), S. 152-155

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ISSN: 0377-0486

Keywords: Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Physics

Notes: The polarized and depolarized Raman spectra of the ν2 (CH2 bend) and ν3 (C—Br stretch) vibrations in dibromomethane have been studied as a function of temperature throughout the liquid range. Reorientational correlation times derived from the two modes were simllar in both magnitude and dependence on temperature. This result, together with other structural data, suggests that the rotational dynamics of this molecule in the liquid phase are quasi symmetric-top in character. Vibrational dephasing times calculated from the two lineshapes were also of the same magnitude. However, modulation times determined via the Kubo lineshpae formalism varied markedly between the vibrations. This provides evidence that vibrational dephasing of the bending and stretching modes are influenced by different intermolecular forces in the liquid.

Additional Material: 3 Ill.