ISSN:
0030-4921
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Phosphorylation of the tetrapeptide Gly-Gly-His-Ala by phosphoamidate provides a model peptide for proteins which, in the course of their reaction, bind a phosphoryl group to an imidazole ring. 31P- and 1H-NMR data, including chemical shift and pK values, for this peptide and its three phospho-derivatives are presented. These data show that it is possible, by NMR studies, to decide whether or not a peptide or a protein is phosphorylated at the N-1 or at the N-3 position of an imidazole ring, and how this information can be achieved.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1270170203
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