ISSN:
0935-6304
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Asymmetrical or tailed peaks are a common problem in chromatography. The causes of this distortion are described and classified. Each case is discussed from the point of view of first diagnosing the cause of asymmetry end then dealing with it appropriately; e.g. by removing the cause or, in applications to physicochemical measurement, by using more appropriate measures of retention than the residence time of the peak maximum. The classification of sources of asymmetry applies to both gas and liquid chromatography, allowing information derived from one field to be extended to the other.Part 1 of this review covers nonlinear, concentration-dependent behavior with and without nonideal band-spreading. Part 2 will deal with sources of distortion controlled by the kinetics of transport or reaction processes, viz. apparatus effects, incomplete resolution, slow kinetic processes, chemical reaction, and column voids.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240050702
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