ISSN:
0749-1581
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The potential of two-dimensional 31P/1H shift correlation NMR spectroscopy is demonstrated on three self-complementary oligodeoxyribonucleotides: [d(CpGpCpG)]2, [d(ApCpGpT)]2 and [d(ApGpCpT)]2. The usefulness of this experiment for the sequential assignments of the nucleotides as a complementary technique to homonuclear shift correlation procedures (e.g. COSY) is outlined. The complete 31P assignments for all three tetramers are given, and are compared with literature data obtained by different approaches. A surprising and, as far as we are aware, previously unreported property of the 4′-protons in the sugar phosphate backbone is described.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260240313
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