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  • Anatomic sections  (1)
  • Key words: Synchrotron – Iodine – Gadolinium – CT – Brain – Glioma  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 9 (1987), S. 95-105 
    ISSN: 1279-8517
    Keywords: Mediastinum ; MRI ; Anatomic sections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé 10 volontaires présentant un médiastin normal ont été explorés en Résonance Magnétique avec un imageur CGR 0,5 Tesla à aimant supraconducteur. La matrice de reconstruction est constituée par une grille de 256×256 pour un champ de l'ordre de 420 mm, soit une résolution spatiale de 1,6×1,6 mm2. Les coupes pondérées en T1 ont été réalisées en synchronisation sur l'ECG. Les coupes sagittales jointives sont corrélées à des coupes anatomiques sagittales réalisées sur un même sujet embaumé et congelé. Coupes IRM et coupes anatomiques sont réalisées tous les 5 mm et sont référencées par rapport au plan sagittal médian du médiastin. Des exemples de variations morphologiques, de malformations ou de tumeurs étudiées en coupes sagittales (extraits des examens de plus de 170 malades) montrent l'intérêt de cette incidence d'exploration.
    Notes: Summary Ten volunteers with a normal mediastinum were investigated by magnetic resonance using a 0,5 Tesla CGR imager with a supraconducting magnet. The reconstruction matrix consisted of a 256×256 grating for a field of the order of 420 mm, with a spatial resolution of 1.6×1.6 mm2. The sections, balanced in T1, were performed in synchronization with the ECG. The successive sagittal sections were correlated with sagittal sections made on a single embalmed frozen subject. The MRI and anatomic sections were made at 5 mm intervals and located in relation to the median sagittal plane of the mediastinum. Examples of structural variations, malformations or tumours studied in sagittal sections, and taken from investigation of over 170 patients, demonstrate the importance of this investigational technique.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Synchrotron – Iodine – Gadolinium – CT – Brain – Glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The purpose of this work was to demonstrate the feasibility of a new imaging technique called synchrotron radiation computed tomography (SRCT). This technique leads to a direct assessment of the in vivo concentration of an iodine- or gadolinium-labeled compound. Rats bearing C6 glioma were imaged by MRI prior to the SRCT experiment. The SRCT experiments were performed after a 1.3 g I/kg (n = 5) or a 0.4 g Gd/kg (n = 5) injection. Finally, brains were sampled for histology. The SRCT images exhibited contrast enhancement at the tumor location. Ten minutes after injection, iodine and gadolinium tissular concentrations were equal to 0.80 ( ± 0.40) mg/cm3 and 0.50 ( ± 0.10) mg/cm3, respectively in the peripheral area of the tumor (respective background value: 0.20 ± 0.02 to 0.10 ± 0.01). Correlation to MRI and histology revealed that the contrast uptake occurred in the most vascularized area of the tumor. The present study summarizes the feasibility of in vivo SRCT to obtain quantitative information about iodine and gadolinium-labeled compounds. Beyond brain tumor pathology, the SRCT appears as a complementary approach to MRI and CT, for studying iodine- and gadolinium-labeled compounds by the direct achievement of the tissular concentration value in the tissue.
    Type of Medium: Electronic Resource
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