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  • 1
    Electronic Resource
    Electronic Resource
    Molecular analysis of the androgen receptor gene in 4 patients with complete androgen insensitivity (1998)
    Springer
    Archives of gynecology and obstetrics 261 (1998), S. 95-100 
    Details
    ISSN: 1432-0711
    Keywords: Key words: Androgen receptor ; Androgen insensitivity syndrome ; Point mutation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Androgen insensitivity syndromes are due to defects in the androgen receptor gene. In this study, we analyzed the androgen receptor gene in four cases with complete androgen insensitivity syndrome. In patient 1, one substitutional mutation [arginine (codon CGC) to cysteine (codon TGC) at position 774] of exon F was identified. This position was located in the hormone binding domain and appeared to be one hot spot of mutations because the mutations at the same position in several unrelated cases were reported before. In patient 2, one substitutional mutation [tyrosine (codon TAT) to cysteine (codon TGT) at position 571] of exon B was identified. This position was located in the DNA binding domain. In patients 3 and 4 (siblings), one substitutional mutation [arginine (codon CGA) to glutamine (codon CAA) at position 752] of exon E was identified. Taken together, these abnormalities might be related to the pathogenesis of complete androgen insensitivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004040050206
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  • 2
    Electronic Resource
    Electronic Resource
    Algal phagostimulants for marine herbivorous gastropods (1988)
    Springer
    Journal of chemical ecology 14 (1988), S. 1405-1416 
    Details
    ISSN: 1573-1561
    Keywords: Phagostimulants ; feeding stimulants ; herbivorous gastropods ; abalone ; Haliotis discus ; Aplysia juliana ; Turbo cornutus ; digalactosyldiacylglycerol ; phosphatidylcholine ; 6-sulfoquinovosyldiacylglycerol ; 1,2-diacylglyceryl-4′-O-(N,N,N-trimethyl)-homoserine ; 1-monoacylglyceryl-4′-O-(N,N,N-trimethyl)-monoserine ; Ulva pertusa ; alga ; glycerolipids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Methanol extracts of the green algaUlva pertusa contain four kinds of glycerolipids that are active as feeding-stimulants for marine herbivorous gastropods. These compounds are digalactosyldiacylglycerol (DGDG), 1,2-diacylglycerly-4′-O-(N,N,N-trimethyl)-homoserine (DGTH), 1-monoacylglyceryl-4'-O-(N,N,N-trimethyl)-homoserine (MGTH), and 6-sulfoquinovosyldiacylglycerol (SQDG). The various gastropods exhibit marked specificity, however, as young abaloneHaliotis discus respond to DGDG and DGTH at minute dosages of 20–30 μg/sample zone, but do not respond to 300 μg of SQDG, which is a phagostimulant for two other kinds of gastropods,Turbo comutus andOmphalius pfeifferi.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01020144
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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