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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Clinical autonomic research 3 (1993), S. 101-105 
    ISSN: 1619-1560
    Keywords: Cardioinhibitory ; Carotid sinus syndrome ; Autonomic function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Autonomic reflexes were investigated in patients with the cardioinhibitory carodid sinus syndrome. Heart rate, blood pressure and forearm blood flow responses were recorded during prolonged head-up tilt, the Valsalva manoeuvre, lower body negative pressure and sequential respiratory cycles in ten patients and nine age-matched controls. The mean maximum R—R interval prolongation during carotid sinus massage was 4.4 s. Three patients had syncope during prolonged head-up tilt. Heart rate and blood pressure responses were similar for patients and controls who completed tilt. Responses to lower body negative pressure and Valsalva manoeuvre were similar for both groups. Respiratory sinus arrhythmia was significantly less marked in patients, 7 bpm (0 to 20 bpm) versus 15 bpm (6 to 35 bpm;p = 0.05). Therefore, neck massage and deep breathing produce abnormal cardiac vagal responses, whereas other reflexes, including response to lower body negative pressure and the Valsalva manoeuvre are within the normal range in cardioinhibitory carotid sinus syndrome.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-6903
    Keywords: Antibody ; myelin ; cerebroside ; multiple sclerosis ; ELISA ; cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The standard ELISA technique was improved for the detection of antigalactocerebroside antibody in biological fluid. Mouse monoclonal antigalactocerebroside antibody was used to demonstrate specificity and sensitivity of the technique. After optimization of the assay, the usefulness of this measurement for the evaluation of patients with multiple sclerosis was assessed. The presence of antigalactocerebroside antibodies in the cerebrospinal fluid of 20 patients with multiple sclerosis, 10 with other neurological diseases and 10 normal individuals was determined. All the CSF samples from normal individuals were negative. In patients with multiple sclerosis 14 of the 20 samples had elevated levels of antigalactocerebroside antibody, whereas with other neurological diseases 5 out of 10 were positive. Antigalactocerebroside levels were lower in samples from patients during an acute relapse than in those from more chronic cases. These results indicate that the presence of anti-galactocerebroside antibody in cerebrospinal fluid is not specific to MS but may reflect previous damage to myelin.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Clinical Anatomy 6 (1993), S. 280-288 
    ISSN: 0897-3806
    Keywords: femur ; anteversion ; ultrasound ; bones ; Life and Medical Sciences ; Miscellaneous Medical
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This study evaluates the most valid and reproducible method for directly measuring anteversion (torsion) in dried femora using a commercially available measuring machine. Each femur was placed horizontally on the surface of the machine and readings were obtained from the head, the shaft distal to the lesser trochanter, and the distal end. Using computer software, four different anteversion angles were calculated: the center head-neck line to the retrocondylar line (Method 1); the center head-neck line to the transcondylar line (Method 2); the anterior head-trochanter line to the retrocondylar line (Method 3); and the anterior head-trochanter line to the transcondylar line (Method 4). The methods were applied to 20 femora, which were measured twice by one observer. The most reproducible method of measuring femoral anteversion uses the bone surfaces on the anterior aspect of the head and greater trochanter and on the posterior aspect of the condyles (Method 3.95% confidence limits of ± 0.4°). The other methods are shown to be reproducible to ±2.4°, ±3.3° and ±1.7° (Methods 1, 2, and 4, respectively, 95% confidence limits). Conversion factors between the different methods are: 12.5° + 0.8 x (anteversion angle) to change each of Method 2 to Method 1 and Method 4 to Method 3; and 8° + 0.7 x (anteversion angle) to change each of Method 1 to Method 3 and Method 2 to Method 4 (correct to within ±3°). © 1993 Wiley-Liss, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Clinical Anatomy 6 (1993), S. 342-348 
    ISSN: 0897-3806
    Keywords: hip ; knee ; femoral anteversion ; tibial torsion ; Life and Medical Sciences ; Miscellaneous Medical
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In this paper, we introduce the concept of functional anteversion of the femur and its positional change. It emerged from studies using B-mode and real-time ultrasound to determine femoral anteversion in two knee positions. Twenty healthy children were scanned at the hips whilst lying supine with knees extended and then with the knees flexed to about 90°. The “anteversion” angle between the head-trochanter line and the horizontal measured with knees extended and feet together is determined by three factors: 1) anatomical femoral anteversion, 2) femoro-tibial rotation at the knee, and 3) tibial torsion. This is one type of “functional anteversion” of the femur.The best reproducibility for functional femoral anteversion was obtained by scanning with real-time ultrasound and the knees extended (95% confidence limits within ± 2.8°); the use of B-mode ultrasound in the knees-extended position is significantly less reproducible (95% confidence limits within ± 6.1°). In the flexed-knee position, the reproducibility is similar with both B-mode and real-time ultrasound (± 2.6-3.5°). Both positions have limitations in attempts to measure anatomical femoral anteversion by ultrasound.The functional femoral anteversion angle measured by B-mode and real-time ultrasound is significantly larger (by 9-10°) with the knees flexed than with the knees extended. This positional change of measured femoral anteversion involving axial rotation at the hip is attributed mainly to 1) lateral rotation (unlocking) of the femur at the knee during flexion from the fully extended position and 2) any lateral tibial torsion which rotates the femur nedially in the knees-extended position with the feet vertical. The considerable individual variation and asymmetry of this axial rotational change may have relevance to the etiology of certain clinical disorders of the spine, hip, and knee joints. © 1993 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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