ISSN:
1432-2072
Keywords:
Antidepressants
;
Chronic treatment
;
Avoidance behavior
;
Desipramine
;
Mianserin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Desipramine or mianserin were given in daily doses of 10 mg/kg during the training period: 5 daily 100-trial sessions in a shuttlebox without pretreatment (“acute groups”), or after pretreatment with the same daily doses for 1 week (short pretreatment) or for 4 weeks (long pretreatment). Acute treatment and short pretreatment with the antidepressants significantly depressed the acquisition of the avoidance reflex, while the learning of mice receiving the long pretreatment remained unimpaired.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00422415
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