ISSN:
1434-9949
Schlagwort(e):
Antinuclear Antibodies (ANAs)
;
Nuclear Dot Pattern
;
Undifferentiated Connective Tissue Disease (UCTD)
;
Autoantigen
;
Tumour
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary Reported is the case of a 60-year-old female who was referred to our rheumatology center because of a high titer of antinuclear antibodies (ANAs). Initially several lupus-like features suggested a diagnosis of undifferentiated connective tissue disease (UCTD). Immunofluorescence of the patient's serum showed a nuclear dot pattern. Counterimmunoelectrophoresis for antibodies to Sm, RNP, SS-A and SS-B were negative. Immunoblotting revealed a band at 53 kD which did not correspond to known autoantigens. Several months later the patient presented to the emergency room with symptoms due to a hypertensive crisis. Check-up finally revealed a cortisone-producing tumour of the right adrenal gland. The adenoma was removed by surgery and the patient did well again.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02208093
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