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  • 1
    ISSN: 1433-0385
    Keywords: Key words: Gastroesophageal reflux disease ; Antireflux surgery ; Minimally invasive surgery ; Endoscopic intervention. ; Schlüsselwörter: Gastrooesophageale Refluxkrankheit ; Antirefluxchirurgie ; minimal-invasive Chirurgie ; endoskopische Intervention.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Eine neue endoskopische, intraluminale Valvuloplastik wird beschrieben. Es handelt sich hierbei um einen einfachen, ambulant durchführbaren Antirefluxeingriff, der bei Patienten mit frühen Stadien der gastrooesophagealen Refluxkrankheit eine Alternative zur lebenslangen medikamentösen Dauertherapie bieten könnte. Die Technik des Eingriffs, die Effektivität und erste Langzeitergebnisse im Tierversuch an Pavianen werden dargestellt.
    Notes: Summary. A new endoscopic intraluminal valvuloplasty is described. The procedure provides a simple, easy outpatient approach for antireflux surgery and is applicable to patients with early gastroesophageal reflux disease as an alternative to chronic life-long medical therapy. The feasibility, durability and efficacy of the procedure in baboons are reported.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Key words Thalamus ; Basal ganglia ; Cerebellum ; Electrical stimulation ; Movement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The motor thalamic areas receiving input from the globus pallidus (VA) and the cerebellar nuclei (VL) appear to have different roles in the generation and guidance of movements. In order to further test these differences, we used electrical stimulation to map the ventro-anterior and ventro-lateral nuclei of the thalamus in three ketamine anaesthetised monkeys. Movements were readily evoked from VL at currents of down to 10 μA. The movements were typically multi-joint, and stimulation could evoke arm and trunk or arm and facial movement at the same current threshold. Evoked arm movements often involved multiple joints, with or without finger movements. Facial movements included the lips, tongue, jaw, eyebrows and, occasionally, the eyes. The thalamic map was topographic, but complex with at least two separate regions related to arm movement. Very few sites within the VA could stimulate movement, even at high currents. We therefore suggest that the cerebellar projections to motor regions of the cortex, which pass through the VL thalamic nuclei, have a different relationship and are closer to movement execution than the projections from basal ganglia via the ventro-anterior nucleus.
    Type of Medium: Electronic Resource
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