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  • 1
    Electronic Resource
    Electronic Resource
    Intraorbital cerebrospinal fluid outflow and the posterior uveal compartment of the hamster eye (1985)
    Springer
    Cell & tissue research 240 (1985), S. 77-87 
    Details
    ISSN: 1432-0878
    Keywords: Cerebrospinal fluid ; Aqueous humor ; Choroid ; Meninges ; Golden hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary An ultrastructural and tracer study was undertaken to determine normal outflow pathways of cerebrospinal fluid (CSF) at the terminal subarachnoid space (SAS) of the optic nerve. In the morphological studies, the optic nerve dura and arachnoid were found to be continuous with the sclera of the eye beyond the optic nerve SAS. The pia mater is continuous with the inner sciera and the lamina fusca of the eye. Montages and serial sections demonstrated that the distal SAS is divided into numerous tortuous channels to form an “arachnoidal trabecular meshwork”. Spaces of this meshwork continue into “microcanals” which bypass the outer arachnoid barrier layers of the optic nerve meninges to reach the sclera and posterior intraorbital connective tissue. Ferritin infused into the cisterna magna entered the optic nerve SAS within 1 min and reached arachnoidal trabecular meshwork channels and the microcanals within 8 min. It then passed into intraorbital connective tissue spaces at the posterior pole of the eye. Ferritin appeared to be blocked by the lamina fusca and a newly discovered “posterior compact zone” which together prevented its entrance into the choroidal interstitium. These observations suggest that a “ subarachnoidal-scleral-orbital outflow pathway” provides a route for CSF drainage from the optic nerve SAS to intraorbital connective tissue. The previously described “posterior uveal compartment” in the hamster eye (Kelly et al. 1983) appears to be relatively isolated from this subarachnoidal-scleral-orbital CSF outflow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217560
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Structural analysis of potential barriers to bulk-flow exchanges between uvea and sclera in eyes of rabbits (1990)
    Springer
    Cell & tissue research 259 (1990), S. 255-263 
    Details
    ISSN: 1432-0878
    Keywords: Choroid, ocular ; Uvea ; Aqueous humor ; Eyes, lateral ; Rabbit (Lagomorpha)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The uveal tract of rabbit eyes was examined using transmission electron microscopy of thin sections and freeze-fracture replicas. Emphasis was placed on the organization of pigmented and fibroblastic cells near the ora serrata and more generally in the lamina fusca, since these regions were previously found to restrict ingress of tracer molecules to the choroid in hamster eyes. There were significant differences between rabbit and hamster in the disposition of the pigmented cells and fibroblastic layers, the extent and patterns of tight junctions adjoining fibroblastic cells, and the presence of vesicles or fenestrations in the attenuated fibroblastic cell processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318447
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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