ISSN:
1619-1560
Keywords:
Myocardial infarction
;
Blood pressure variability
;
Arterial blood pressure
;
Autonomic nervous function
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The aim of the study was to assess non-invasively circadian blood pressure rhythm as well as the influence of parasympathetic function 2 and 6 weeks after acute myocardial infarction treated with beta-blocking agents. Twenty-four patients with uncomplicated first myocardial infarction, and aged less than 60 years, underwent ambulatory blood pressure recordings every 15 min during the day (0900–2100 h) and every 30 min during the night (2100–0900 h), 2 and 6 weeks after infarction. The deep breathing test (6 breaths/min) was performed on each occasion. Normal circadian blood pressure rhythm was maintained with a nocturnal decline of 10 to 15%. Both for systolic and diastolic blood pressure a moderate increase was obtained after 6 weeks (107.8 ± 9.2 mmHg vs. 111.8 ± 10.3 mmHg; NS and 64.9 ± 4.5 mmHg vs. 68.8 ± 6.5 mmHg;p 〈 0.05). The respective blood pressure variations were significantly higher at that time (10.0 ± 2.4 mmHg vs. 13.6 ± 4.2 mmHg;p 〈 0.001 and 7.9 ± 1.7 mmHg vs. 11.7 ± 3.5 mmHg,p 〈 0.001). There was a close correlation (r=0.60,p 〈 0.005) between 24-h diastolic blood pressure variability and the results of the parasympathetic function test (deep breathing) 2 weeks after infarction. We conclude that the circadian blood pressure rhythm persists after acute myocardial infarction. The correlation between blood pressure variability and parasympathetic function early after infarction suggests a role for vagal control in post-infarction blood pressure variability.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01829015
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