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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 31 (1978), S. 445-457 
    ISSN: 1432-1106
    Keywords: Superior colliculus ; Visual cortex ; Visually-guided locomotion ; Orienting reflex
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rats with either bilateral ablations of superior colliculus, bilateral ablations of visual cortex, or sham operations were trained to run across a large arena towards a small illuminated target which varied in location from trial to trial. An impairment in this visually-guided running was apparent in the cortical group, but not in the collicular group. When, in a second experiment, the spatial relationships within the apparatus were changed by extending the entry-tunnel some distance into the arena, the running of the cortical group became even more impaired, while the collicular animals continued to run towards the targets under efficient visual control. In a third experiment, the effect of introducing a novel flashing light in various locations around the perimeter of the arena was investigated. It was found that unlike the other two groups, the collicular animals showed no orienting reflex to the novel stimulus when it was presented outside a broad central area of the visual field.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 56 (1984), S. 106-114 
    ISSN: 1432-1106
    Keywords: Vision ; Distractibility ; Rats ; Orienting ; Superior colliculus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rats with bilateral lesions of the superior colliculus (SC) or with sham operations were trained on a modified version of the running task of Goodale and Murison (1975). The rats were required to shuttle between two large boxes, one of which required a choice between 5 doors, the other having only 1 door. A flashing distractor light at the side of a box was subsequently presented on once-daily test trials. For half the rats of each group these tests were given at 1 month and for the others at 3 months post-operatively. In agreement with previous studies, the SC-lesioned rats showed an abolition of orienting reactions to the distractor. (This was so in both boxes, i.e. a lower attentional load in the running task failed to alleviate the SC lesion-induced deficit.) However, only in the early-tested rats did the lesion cause a loss of freezing response to the distractor. Since in the late-tested group the rats froze but did not orient, it is suggested that the orienting loss at least in their case cannot be attributed to a partial visual field defect.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 150 (1991), S. 448-449 
    ISSN: 1432-1076
    Keywords: Asthma ; Beclomethasone ; Inhaled corticosteroids side-effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to normal. This report indicates that there are some children who are at risk of developing side-effects on doses of inhaled topical steroids normally considered to be entirely safe.
    Type of Medium: Electronic Resource
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