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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 23 (1996), S. 213-225 
    ISSN: 1619-7089
    Keywords: Body-composition methodology ; Cirrhosis ; Fat ; Fat-free mass ; Multi-component models
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Very little information is available on body composition in patients with cirrhosis. Difficulties arise in studying these patients because they tend to retain fluid and this results in changes in tissue density and in the hydration fraction of fat-free mass. As the classic body composition techniques rely on the assumption that these variables remain constant, use of these methods will result in either under- or overestimates of body composition variables. Use of multi-component models, employing two or more measurement techniques, will obviate the need for some of the assumptions inherent in the use of single techniques, thereby increasing the accuracy of the assessments, without loss of precision.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Metabolic brain disease 13 (1998), S. 273-290 
    ISSN: 1573-7365
    Keywords: Astrocytes ; encephalopathy ; hepatic ; globus pallidus ; liver cirrhosis ; liver failure ; Magnetic Resonance Imaging ; manganese ; portal-systemic shunt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Bilateral, symmetrical hyperintensity of the globus pallidus is observed in T1-weighted cerebral magnetic resonance images in from 52 to 100% of patients with chronic liver disease. No significant relationship exists between the presence of these cerebral changes in image signal intensity and the patients' neuropsychiatric status. However, their presence significantly relates to both the severity of the liver disease and the presence and degree of portal-systemic shunting of blood. This shortening of the T1-relaxation time is associated with pallidal deposition of manganese most likely reflecting the presence of an adaptive process designed to improve the efficacy of ammonia detoxification by astrocytes. Future studies employing magnetic resonance imaging techniques to obtain information on cerebral function or combined with magnetic resonance spectroscopy to obtain localized biochemical information might further our understanding of the pathogenesis of hepatic encephalopathy in cirrhotic patients.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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