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  • Atmospheric Pollution  (1)
  • Chemistry  (1)
  • Methanol dehydrogenase  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Epidemiological investigations in the Netherlands into the influence of smoking and atmospheric pollution or respiratory symptoms and lung function disturbances (1973)
    Springer
    Lung 149 (1973), S. 119-126 
    Details
    ISSN: 1432-1750
    Schlagwort(e): Atmospheric Pollution ; Lung Function Disturbances
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Results of epidemiological cross-sectional studies of chronic non-specific lung diseases (CNSLD) in the Netherlands suggest that the exogenous factors smoking and atmospheric pollution have an effect on chronic production of phlegm. These factors seemed to have no effect on bronchial obstruction, except in one subgroup of men, in whom there was a relationship between the exogenous factors and the prevalence of dyspnoea, although no relationship was found between these factors and impairment of FEV1. The implications of the findings are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02151747
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  • 2
    Digitale Medien
    Digitale Medien
    Environmental regulation of alcohol metabolism in thermotolerant methylotrophic Bacillus strains (1992)
    Springer
    Archives of microbiology 157 (1992), S. 272-278 
    Details
    ISSN: 1432-072X
    Schlagwort(e): Bacillus ; Thermotolerance ; Methylotrophy ; Methanol dehydrogenase ; Activator protein ; RuMP cycle of formaldehyde fixation ; Hexulose-6-phosphate synthase ; Continuous culture ; Methanol limitation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The thermotolerant methylotroph Bacillus sp. C1 possesses a novel NAD-dependent methanol dehydrogenase (MDH), with distinct structural and mechanistic properties. During growth on methanol and ethanol, MDH was responsible for the oxidation of both these substrates. MDH activity in cells grown on methanol or glucose was inversely related to the growth rate. Highest activity levels were observed in cells grown on the C1-substrates methanol and formaldehyde. The affinity of MDH for alcohol substrates and NAD, as well as V max, are strongly increased in the presence of a M r 50,000 activator protein plus Mg2+-ions [Arfman et al. (1991) J Biol Chem 266: 3955–3960]. Under all growth conditions tested the cells contained an approximately 18-fold molar excess of (decameric) MDH over (dimeric) activator protein. Expression of hexulose-6-phosphate synthase (HPS), the key enzyme of the RuMP cycle, was probably induced by the substrate formaldehyde. Cells with high MDH and low HPS activity levels immediately accumulated (toxic) formaldehyde when exposed to a transient increase in methanol concentration. Similarly, cells with high MDH and low CoA-linked NAD-dependent acetaldehyde dehydrogenase activity levels produced acetaldehyde when subjected to a rise in ethanol concentration. Problems frequently observed in establishing cultures of methylotrophic bacilli on methanol- or ethanol-containing media are (in part) assigned to these phenomena.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00245161
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  • 3
    Digitale Medien
    Digitale Medien
    Introductory remarks (1979)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 19 (1979), S. 65-65 
    Details
    ISSN: 0032-3888
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pen.760190202
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