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  • Auranofin  (1)
  • CH3OH  (1)
  • FIR Laser Lines  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Acoustooptic extension of the frequency tunability of CW CO2 lasers: New FIR lasers emissions from CH3OH and13CH3OH (1991)
    Springer
    International journal of infrared and millimeter waves 12 (1991), S. 449-471 
    Details
    ISSN: 1572-9559
    Keywords: waveguide CO2 lasers ; new FIR laser lines ; CH3OH ; 13CH3OH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have increased the frequency tunability of our CW waveguide CO2 lasers by means of an acoustooptic amplitude modulator, operating at the fixed frequency of 90 MHz. The up-shifted, or down-shifted, laser optical sideband can be generated independently by adjusting the orientation of the modulator. The efficiency is larger than 50%. The frequency tunability of the CO2 laser around each laser line is thus increased by 180 MHz. To demonstrate the possibilities of this method, a source composed of the above modulator and of a CW, 300 MHz tunable waveguide CO2 laser has been used for the search of new large offset FIR laser lines from optically pumped CH3OH and13CH3OH molecules. As a result 15 and 10 new large offset laser lines were discovered respectively. New assignments of some laser lines are also proposed. We have also measured the Stark effect, the offset, and the polarization of other already known lines. In particular a Stark effect frequency tuning of about 1 GHz is demonstrated for a laser line at 208.399 μm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01010879
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A review of optically pumped far-infrared laser lines from methanol isotopes (1994)
    Springer
    International journal of infrared and millimeter waves 15 (1994), S. 1-44 
    Details
    ISSN: 1572-9559
    Keywords: FIR Laser Lines ; Methanol's Isotopes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The technique of optical pumping in polar molecules is the most efficient for Far-Infrared (FIR) laser generation, providing also a versatile and powerful tool for molecular spectroscopy in this spectral region. Methanol (CH3OH) and its isotopic varieties are the best media for optically pumped FIR laser, with over thousand lines observed, and the most widely used for investigations and applications. In this sense, it is important organize and make available catalogues of FIR laser lines as complete as possible. Since the last critical reviews of 1984 [1] on methanol and its isotopic varieties [2,3,4], over hundred papers have been published dealing with hundreds of new FIR laser lines. In 1992 a review of FIR laser lines from CH3OH was presented [5]. In this communication we extend this work to the other methanol isotopes, namely CH3OD, CD3OH, CD3OD,13CH3OH,13CD3OH,13CD3OD, CH3 18OH, CH2DOH, CHD2OH and CH2DOD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02265874
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of oral gold salt therapy on bile acid absorption in rheumatoid arthritis patients (1990)
    Springer
    Clinical rheumatology 9 (1990), S. 42-47 
    Details
    ISSN: 1434-9949
    Keywords: Auranofin ; Serum Conjugated Bile Acids ; Rheumatoid Arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several studies pointed out an altered stool pattern as the most common side effect of auranofin therapy. The major mechanism in the aetiology of auranofin-induced impairment in bowel habit seems to be the inhibition of Na+/K+ A TPase in the gut. In vitro experiments proved that auranofin can affect active bile acid (BA) reabsorption in rat terminal ileum; this action, due to the ability of the drug to reduce Na+ pump activity by inhibiting Na+/K+ATPase, may make a significant contribution to the auranofininduced diarrhoea. The ability of auranof in to reduce the Na+ gradient necessary for active BA reabsorption, however, could cause a decrease of serum BA levels in patients taking auranofin before or without the development of an overt diarrhoea. We measured fasting and postprandial serum conjugated BA levels in 10 female rheumatoid arthritis patients before and after one month and two months' auranofin treatment. No patient developed diarrhoea during the chrysotherapy. When oral gold salt therapy was started, we observed a slight decrease in serum BA levels, but difference was not statistically significant. We can conclude that auranofin therapy does not cause BA malabsorption in patients who do not develop diarrhoea during the treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02030239
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    Paper (German National Licenses)
    Fulltext
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