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  • Autologes Venentransplantat  (1)
  • MRI  (1)
  • Opioid analgesics  (1)
  • 1
    ISSN: 1420-908X
    Keywords: Superoxide ; Nociception ; Opioid analgesics ; Potentiation of antinociception ; Animals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The study examined the potentiation of the antinociceptive action of opioid analgesics produced by gaseous superoxide (GS) in the rat hind paw withdrawal test (PWT) and by GS or hydrogen peroxide (HP) in the formalin test. In the PWT, inhalation of GS for 50 minutes before i.p. injection of threshold doses of morphine (0.5mg/kg) and trimeperidine (1.0 mg/kg) increased the threshold of nociception (TN) by a maximum of 43.0% (p〈0.05) and 113.4% (p〈0.01) respectively. The GS/trimeperidine-dependent increase in TN showed two peaks, the second of which could be suppressed by nialamide. Naloxone abolished the GS/morphine-dependent increased in the TN. In the formalin test, a significant antinociceptive effect developed after GS inhalation or HP administration (intranasally, 2×5μl of 2×10−5 mol/l solution in saline) in combination with low doses of Omnopon (0.06–0.75 mg/kg). These results suggest that both GS and HP potentiate the antinociceptive effects of opioid analgesics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: MEG ; MRI ; Localization methods ; P100-P200 ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of this study was to compare the relative efficacy of two methods in assessing the location of the sources of the N100 and P200 components of evoked magnetic fields (EMFs) to transient tone stimuli. EMFs to left ear stimulation, containing both components, were recorded over the right hemisphere of six normal subjects. The magnetic scalp distributions calculated at several adjacent time points, covering the duration of each component's peak, were used to estimate the source parameters of each component. Good estimates of the source of both components were obtained from all magnetic field distributions. The averaged spatial parameters derived from all distributions of each component as well as the parameters derived from the distribution that gave the best source estimate for each component were projected onto magnetic resonance images of subject's head. It was found that the source of each component is located on the superior surface of the temporal lobe and that the source of the P200 component is anterior to the N100 source in all subjects using both procedures.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 155 (1971), S. 128-133 
    ISSN: 1591-9528
    Keywords: Spleno-pulmonary shunt ; Portal hypertension ; Autologous venous transplant ; Spleno-pulmonaler Shunt ; Portale Hypertension ; Autologes Venentransplantat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird eine Methode zur Ableitung des Bauchraumblutes über die Milzvene in die linke Lungenunterlappenvene unter Zwischenschaltung eines autologen Venentransplantats beim Hund angegeben. Die Versuchsanordnung ermöglicht die Abklärung kreislaufdynamischer und stoffwechselbedingter Vorgänge bei der Einleitung des Pfortaderblutes in den großen Kreislauf unter Umgehung des rechten Herzens und der Lungenpassage. Therapeutische Indikationen eines solchen Vorgehens sind Formen des Budd-Chiari-Syndroms und eine Aplasie der Vena cava inferior mit portaler Hypertension und blutenden Oesophagusvaricen.
    Notes: Summary A spleno-pulmonary by-pass operation by means of an autologous venous transplant is described. The end-to-end anastomosis for the prolongation of the splenic vein and the end-to-side anastomosis of the transplanted vein to the left pulmonary vein is done with the Kunlin-ring method. The experiment allows the observation of circulatory and biochemic changes as a consequence of the portal blood deviation into the left auricle. Clinical indications for this method are the Budd-Chiari syndrome and the aplasia of the inferior caval vein with portal hypertension and bleeding esophageal varices.
    Type of Medium: Electronic Resource
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