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  • Autologous  (1)
  • Best. von Molybdän in Eisen, Stahl  (1)
  • Brush border  (1)
  • 1
    ISSN: 1432-0584
    Keywords: Nonfrozen ; Marrow ; Autologous ; Transplantation ; Lymphomas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To investigate the impact of frozen and nonfrozen bone marrow on engraftment kinetics and disease outcome, 94 patients with non-Hodgkin's lymphoma (NHL) autografted with frozen marrow (F group) were retrospectively compared with 38 who received marrow stored at 4° C or 10° C (NF group). The major end points of this study were time to hematopoietic recovery and early toxicity; disease response, diseasefree survival (DFS), and relapse rate were also analyzed. Upon comparison of the NF and F groups, no significant differences were found in the period of time required to achieve a granulocyte count higher than 0.5×109/l (20 and 22 days, respectively,p=0.47) or a platelet count higher than 20×109/l (28 and 27 days, respectively,p=0.54). In addition, both groups behaved similarly in respect to toxic death (NF group 13%, F group 22%,p=0.36), response rate (complete remission rate 78% in both groups), DFS (NF group 48%, F group 49%,p=0.66), and relapse rate (NF group 30, F group 19%,p=0.37). This study confirms that nonfrozen bone marrow is useful to support patients with NHL treated with myeloablative therapies.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Key words Adenosine receptors ; Nucleoside transport ; Sodium-coupled adenosine transport ; Hypothyroidism ; Brush border
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Studies of the uptake of [3H]adenosine ([3H]ADO) were performed using brush border membrane vesicles (BBMV) from normal (N) and hypothyroid (Tx) rat kidneys, to test if decreased Na+ reabsorption in hypothyroidism might be associated with abnormalities in ADO transport. [3H]ADO uptake (1–10 μmol) for both conditions was measured in the presence of Na+ (10–150 mmol/l); the effects of dipyridamole (10 μmol/l) and 1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine (PACPX, 10 μmol/l) were also studied. Na+-stimulated ADO uptake was decreased in Tx BBMV. Michaelis–Menten constants showed a decreased ADO carrier affinity (K m 2.46 ± 0.14 in N, vs K m 4.46 ± 0.88 μmol/l in Tx, P〈0.05), with no change in the number of carriers (V max 295 ± 25 in N, vs 229.2 ± 56 pmol·min–1·mg protein in Tx). Na+ affinity remained unchanged (K Na+ 11.5 ± 3.5 in N, vs K Na+ 12.72 ± 0.7 mmol/l in Tx). Inhibition of Na+-dependent ADO transport was 50% in N as opposed to 58% in Tx with dipyridamole, and 72% in N versus 47% in Tx with PACPX. These results suggest that decreased Na+-dependent ADO cotransport contributes to the diminished tubular reabsorption that occurs in hypothyroidism.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 264 (1973), S. 139-142 
    ISSN: 1618-2650
    Keywords: Best. von Molybdän in Eisen, Stahl ; Śpektralphotometrie ; Zinn(II)-chlorid als Reduktionsmittel, Thiocyanatkomplex
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary A new procedure is proposed for the photometric determination of molybdenum in iron and steels using thiocyanate and tin(II) chloride solution [in glycerol-ethannol (3∶1) or in diethylenglycol] as a reducer and extraction with n-butyl acetate. Beer's law is obeyed between 0.2 and 80 μg Mo/ml. The minimum photometric error is 3.2%, the molar absorptivity is 15640 at 470 nm and the best concentration range for determination is between 0.6 and 6 μg Mo/ml.
    Notes: Zusammenfassung Das vorgeschlagene Verfahren beruht auf Bildung des Thiocyanatkomplexes unter Verwendung von Zinn(II)-chlorid als Reduktionsmittel [in Glycerin/Äthanol (3∶1) oder Diäthylenglykol]. Als Extraktionsmittel dient n-Butylacetat. Das Beersche Gesetz wird im Bereich 0,2–80 μg Mo/l befolgt. Der kleinste photometrische Fehler beträgt 3,2%, die molare Extinktion 15640 bei 470 nm und der optimale Konzentrationsbereich 0,6–6 μgMo/l.
    Type of Medium: Electronic Resource
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