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Digitale Medien

Histopathological findings in the central and peripheral nervous systems in neuroborreliosis (1990)

Meurers, B. ; Kohlhepp, W. ; Gold, R. ; [weitere]

Springer

Journal of neurology 237 (1990), S. 113-116

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Details

ISSN: 1432-1459

Schlagwort(e): Neuroborreliosis ; Vasculitis ; Parenchymal infiltration ; Axonal degeneration ; Monoclonal antibodies

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Very little is known about tissue changes and pathophysiological mechanisms in Garin-Boujadoux-Bannwarth syndrome. We report histopathological findings in the central and peripheral nervous systems of three typical cases. In the acute stage of the disease mononuclear perivascular infiltrations with mainly T-helper cells were the prominent finding, whereas after treatment there was no vessel involvement. The fibre changes in the peripheral nervous system consisted of axonal degeneration. No Borrelia burgdorferi-specific antigen could be detected by immunohistochemical methods. Thus vasculitis might be one of the primary pathophysiological mechanisms for the involvement of the nervous system.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00314674

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