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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 12 (1996), S. 44-48 
    ISSN: 1437-9813
    Keywords: Ureteroceles ; Management
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The treatment of ureteroceles in children requires an individualised approach. Antenatal diagnosis is the ideal, so that postnatal urinary antibiotic prophylaxis and appropriate investigations can be organised. Postnatal investigations should assess both upper and lower urinary tract. Renal and bladder ultrasound and radiographic micturating cystourethragraphy under antibiotic cover will both detect vesicoureteric reflux and assess any bladder outlet obstruction due to the ureterocele. Renal function, particularly of the upper moiety, is best evaluated by technetium Tc99m dimercaptosuccinic acid renal scan. Both function and obstruction can be quantitated by the Tc99m-mercaptoacetyltriglycine isotope scan with intravenous volume expansion (10 ml/kg) and furosemide diuresis (1 mg/kg). Intravenous urography provides the best anatomic information when the upper moiety is functional. The surgical management is based on the clinical situation, which is often variable, and therefore needs to be tailored for each patient. The general principles include restoration of anatomy to as near normal as possible and preservation of functional renal tissue.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 12 (1996), S. 44-48 
    ISSN: 1437-9813
    Keywords: Key words Ureteroceles ; Management
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The treatment of ureteroceles in children requires an individualised approach. Antenatal diagnosis is the ideal, so that postnatal urinary antibiotic prophylaxis and appropriate investigations can be organised. Postnatal investigations should assess both upper and lower urinary tract. Renal and bladder ultrasound and radiographic micturating cystourethragraphy under antibiotic cover will both detect vesicoureteric reflux and assess any bladder outlet obstruction due to the ureterocele. Renal function, particularly of the upper moiety, is best evaluated by technetium Tc99m dimercaptosuccinic acid renal scan. Both function and obstruction can be quantitated by the Tc99m-mercaptoacetyltriglycine isotope scan with intravenous volume expansion (10 ml/kg) and furosemide diuresis (1 mg/kg). Intravenous urography provides the best anatomic information when the upper moiety is functional. The surgical management is based on the clinical situation, which is often variable, and therefore needs to be tailored for each patient. The general principles include restoration of anatomy to as near normal as possible and preservation of functional renal tissue.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    ISSN: 1569-8041
    Keywords: BCL-2 ; BCL-6 ; Burkitt lymphoma ; Burkitt-like lymphoma ; large B-cell lymphoma ; non-Hodgkin's lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Introduction:Burkitt-like lymphoma (BLL) is a provisionalcategory of B-cell lymphoma which is morphologically intermediate betweenBurkitt lymphoma (BL) and large B-cell lymphoma (LBCL). The clinicalsignificance of this morphology is controversial. Patients and methods:We examined 41 cases of pediatric B-celllymphoma by immunohistochemistry for proteins associated with proto-oncogenesc-myc, BCL-2and BCL-6and a subset of cases (withadequate slides) for a proliferation-associated marker (Ki-67) and forapoptosis (Apop-Tag). Sixteen cases of BLL, thirteen cases of BL and twelvecases of LBCL were examined. Results:Our results showed BCL-6expression in 16 of 16BLL, 4 of 13 BL, and 9 of 12 LBCL; c-mycexpression in 14 of 15 BLL,9 of 13 BL, and 12 of 12 LBCL; and BCL-2expression in 2 of 16 BLL,0 of 13 BL, and 6 of 12 LBCL. Mean apoptotic index for BLL was 10.3%(n = 6); for BL was 17.1% (n = 5); and for LBCL was10.9% (n = 6). Ki-67 was diffusely reactive in all casestested. There was a significantly higher proportion of BLL than BL whichexpressed BCL-6(P = 0.0001). Conclusions:Labeling for BCL-6distinguishes BLL fromBL. It is likely that in children in North America, BLL is biologicallydistinct from BL and more closely resembles a subset of LBCL.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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