ISSN:
1573-7373
Keywords:
polyomaviruses
;
BKV
;
JCV
;
brain tumors
;
polymerase chain reaction
;
PCR
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Brain tumors, primarily glioblastoma multiforme, were examined for the presence of BKV DNA. DNAs extracted from 33 fresh-frozen tumors and from an additional 47 paraffin-embedded tumor tissues were tested for BKV sequences using two different primer pairs. One primer pair amplified highly conserved sequences in the early region coding for BKV and JCV T antigens. The other primer pair amplified the regulatory region of BKV-IR, a variant previously associated with human brain tumors. None of the tumors were positive for BKV or JCV DNA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01057961
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