ISSN:
1432-1416
Keywords:
Bacteriophages
;
Nucleotide sequence
;
Spatial Markov chains
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Mathematics
Notes:
Summary The nucleotide sequence of the RNA of the bacteriophage MS2 was examined by computer for internal patterns. We used a technique which analyzes a nucleotide sequence as a Markov chain. This led us to discover patterns within the translated and untranslated regions of the RNA in addition to those patterns formed by the codons. One of the more surprising results of this analysis was the discovery that the non-coding sequences in the genome are as highly ordered, although in a different sense, as the genes themselves. Also of interest was the discovery that the codon frequency distributions for the three genes are similar.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00275725
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