ISSN:
1434-4475
Keywords:
[C-C-C]+[N-O]-addition
;
1,2-Oxazoles
;
13C NMR data
;
fragmentation pattern
;
MS-data
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary 3-Amino-2,4-pentadienthioamides, which were obtained from 6-dialkylamino-2H-thiopyrane-4(3H)iminium halides by alkali hydrolysis, react with hydroxylamine hydrochloride in a [C-C-C] + [N-O]-addition to give selectively 5-amino-3-alkenyl-1,2-oxazoles. These oxazoles have been identified by13C and1H NMR spectroscopic analysis. The configuration of these compounds was established on the basis of the coupling constants and 2D-NOESY-experiments. The position of the substituents has been determined by analysis of the fragmentation pattern.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00811850
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