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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Urological research 20 (1992), S. 281-284 
    ISSN: 1434-0879
    Schlagwort(e): Prostate fluid ; Testosterone ; Dihydrotestosterone ; Zinc ; Benign prostatic hyperplasia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In an attempt to determine whether the androgen profiles of the prostate fluid (EPS) mirror the concentrations in the prostate tissue, we have measured testosterone and dihydrotestosterone (DHT) in EPS and correlated their levels to the concentrations found in hyperplastic prostate tissue (BPH) obtained from the same 19 patients. Although androgen concentrations in EPS were very high (testosterone=106.7±81.9 ng/g dry weight; DHT=54.2±11.2 ng/g dry weight), they did not reflect the concentrations measured in BPH tissue (testosterone=7.56±1.54 ng/g dry weight; DHT=10.54±0.63 ng/g dry weight). Additionally the accumulation of tissular DHT usually associated with BPH was not mirrored in the EPS specimens which demonstrated a relatively higher concentration of testosterone when compared to DHT. In EPS, there was also a very strong correlation between testosterone and DHT concentrations (r=0.89; P〈0.01). We have also measured zinc concentrations in EPS and BPH tissue but were unable to detect any relationship between the two parameters. Significantly, however, EPS zinc concentrations showed a close correlation with EPS testosterone (r=0.73; P〈0.01) and DHT (r=0.69; P〈0.01) concentrations.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European journal of applied physiology 55 (1986), S. 405-409 
    ISSN: 1439-6327
    Schlagwort(e): Cortisol ; Iron ; Maximal oxygen consumption ; Performance ; Endurance exercise
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary As very few of the competitors in a triathlon are truly specialist in more than one of the three disciplines, high levels of physical (and mental) stress may result during the course of the event. We investigated some of the physiological responses occurring in runners participating in an “Iron Man” triathlon consisting of canoeing (20 km), cycling (90 km) and running (42 km), in that sequence. Twenty-one male entrants volunteered as subjects for the study. Prior to the competition, maximal oxygen consumption ( $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ ) was determined. Basal venous blood samples were collected on the day prior to the competition and post-exercise venous blood samples were collected within 5 minutes of completion of the race. Serum iron was significantly reduced from a mean basal value of 20.6 Μmol · l−1 to a mean value of 8.4 Μmol · l−1 after the race. Cortisol levels showed a 3 fold increase after the race. Gross $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (l · min−1) and mass standardised $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1) were both negatively correlated to cortisol levels after the race (p〈0.05). Total performance time was not related to gross $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (l · min−1) but was well correlated to mass corrected $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1). The marked fall in serum iron may have been related to heavy sweating or prelatent iron deficiency. Chronic iron deficiency (without frank anaemia) can impair physical performance, although we were unable to show any significant correlation between serum iron level after the race and time taken to complete the event. The subjects with a lower $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1) had a higher cortisol concentration. In spite of a longer performance time, these subjects were apparently still exposed to greater physiological strain.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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