ISSN:
1434-0879
Keywords:
Creatine kinase (BB)
;
Prostatic acid phosphatase (PAP)
;
Radioimmunoassay
;
Prostatic cancer
;
Benign prostatic hyperplasia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Creatine kinase isoenzyme (CK-BB) measured by mass was used to determine its value in the early diagnosis of prostatic cancer. Sera of patients with prostatic carcinoma of various stages (treated and untreated) were compared to normal male sera and sera of patients with benign hyperplasia of the prostate (BPH) with respect to CK-BB. The sera were simultaneously tested for PAP content. The sensitivity of the CK-BB-RIA was 1.63+/-0.08 μg/l and reproducibility in the higher and lower concentration range 7.6% and 10.5%, respectively. CK-BB alone or in combination with PAP is no marker for early detection of prostatic cancer. In individual cases changes occurred similar to those found with a malignant growth of the prostate.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00262406
Permalink
