ISSN:
1432-0584
Keywords:
Beta 2 microglobulin
;
Acute myeloid leukemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Serum β2 microglobulin levels, measured by radioimmunoassay (Phadebas test), were found increased in acute myeloid leukemias at diagnosis. Serum β2 microglobulin levels were significantly higher in patients with monocytic leukemias (13 patients, M4–M5 FAB classification) than in those with other cytological types (18 patients). β2 microglobulin levels at diagnosis were correlated with serum lysozyme levels, but they were not correlated with blood blast counts, serum LDH and ferritin levels. 195 serum β2 microglobulin measurements were made serially in 30 patients with acute myeloid leukemias in first remission. Compared to values at diagnosis, β2 microglobulin levels in remission were significantly decreased. Out of 30 patients in remission 12 had increased serum β2 microglobulin levels (〉3 mg/l). Serial measurements were not predictive for relapses.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00319813
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