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  • Biceps tendon  (1)
  • Infektion  (1)
  • Islet amyloid polypeptide  (1)
  • 1
    ISSN: 1432-0428
    Keywords: Islet amyloid polypeptide ; Type 2 (non-insulindependent) diabetes mellitus ; polymerase chain reaction ; direct sequencing ; maturity onset diabetes mellitus of the young (MODY) ; Pima Indian
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Islet amyloid polypeptide is the major protein component of the islet amyloid of patients with Type 2 (non-insulin-dependent) diabetes mellitus. Since the synthesis of a structurally abnormal or mutant protein may contribute to the formation of amyloid deposits, we have examined the possibility that a mutant form of islet amyloid polypeptide or its precursor contributes to the formation of islet amyloid in Type 2 diabetic patients. We have sequenced the islet amyloid polypeptide precursor coding regions of the gene of 25 patients with Type 2 diabetes. Genomic DNA fragments corresponding to exon 2 and 3 of the islet amyloid polypeptide gene were amplified from patients' peripheral blood leucocyte DNAs using the polymerase chain reaction and specific oligonucleotide primer sets, and then directly sequenced. The nucleotide sequences of the amplified regions of both alleles of the islet amyloid polypeptide gene of these 25 patients were identical to one another and to the sequence of an islet amyloid polypeptide allele isolated from a human fetal liver genomic library. These findings suggest that a primary structural abnormality of islet amyloid polypeptide or its precursor is unlikely to play a significant role in the formation of islet amyloid in Type 2 diabetic patients.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 375 (1990), S. 19-23 
    ISSN: 1435-2451
    Keywords: Biceps tendon ; Labrum glenoidale ; Sulcus bicipitalis ; Phylogenesis ; Anatomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die polarisationsoptische and histologische Untersuchung des oberen Bicepssehnenabschnittes an 26 Schultern bestätigt, daß die Sehne ihren Ursprung nicht nur, wie allgemein angenommen, am Tuberculum supraglenoidale hat, sondern außerdem γ-förmig im Labrum glenoidale. Dieser Befund kann phylogenetisch erklärt werden. Im weiteren Verlauf der Sehne können neue Befunde im Bereich des Sulcus bicipitalis erhoben werden. Hier ist regelmäßig ein Mesotenonium nachweisbar, das durch einen bindegewebigen Ausläufer an Sulcusdach oder -grund befestigt ist. Darüberhinaus wird gezeigt, daß das Sulcusdach nicht als Ligament (Ligamentum transversum humeri) anzusprechen ist, es handelt sich vielmehr um Ausläufer der Kollagenfasern von Subscapularis- bzw. Kapselansatz am Tuberculum minus.
    Notes: Summary 26 shoulders are studied by polariscopic and histologic examination. It can be confirmed that the origin of the long biceps tendon is not only at the supraglenoid tubercle, but also γ-shaped in the glenoid labrum. This finding can be explained by phylogenetic means. Further details are found during the course of the tendon through the bicipital groove. A mesotenonium is seen regularly. This is fixed either to the roof or the ground of the sulcus by a band of connective tissue. It is shown also, that the roof of the groove is not a ligament (ligamentum transversum. humeri) but consists of collagen fibers continuing from the subscapularis and capsular attachment at the lesser tubercle.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 557-557 
    ISSN: 1435-2451
    Keywords: Abdominal drainage ; Contamination ; Infection ; Bauchhöhlendrainage ; Kontamination ; Infektion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einer prospektiven Studie bei 212 Patienten mit aseptischen und bedingt aseptischen Operationen wurden intra- und postoperativ Abstriche vom Drainzielgebiet und Wunddrain zur bakteriologischen Untersuchung entnommen. Während bei aseptischen Eingriffen in 13%, bzw. bei bedingt aseptischen Eingriffen in 54% ein positiver bakterieller Befund am Operationssitus festgestellt wurde, fand sich postoperativ am Wunddrain in 18% bzw. 32% ein positiver Keimnachweis. Die Analyse der Keimarten erlaubt die Vermutung, daß eine Migration von Hautkeimen durch das Wunddrain möglich ist.
    Notes: Summary In a prospective study on 212 patients who had aseptic and conditioned aseptic operations, smears from the region of drainage and from the drainage material itself were taken per- and postoperatively. Whereas bacterial contamination was found in 13% and 54% of the aseptic and conditioned aseptic operations respectively during surgery, 18% and 32% revealed positive proof of bacterial infection postoperatively. From the analysis of the type of bacteria it can be assumed that migration of bacteria from the skin through the drainage tube can occur.
    Type of Medium: Electronic Resource
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