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  • 1
    ISSN: 1437-9813
    Keywords: Bile duct abnormalities ; Bile duct diseases ; Caroli's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Congenital cystic dilatation of the intrahepatic biliary ducts has been infrequently recognized in childhood. The majority of cases present with dilatation of both the intrahepatic and extrahepatic biliary systems. This report describes a 7-year old boy presenting with hepatomegaly and fever. Computed tomography, ultrasonography, ERCP, and hepatic scintigraphy demonstrated bilobar intrahepatic cystic dilatation of the biliary tract with a normal extrahepatic system. The symptoms were immediately alleviated by a short course of antibiotics. Nevertheless, the patient is at risk for recurrent infection, malignancy, and hepatic failure and is awaiting an appropriate operative solution for his extremely rare anomaly.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2568
    Keywords: prostaglandins ; duodenal ulcer ; arbacet
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The efficacy of arbacet (a synthetic analog of prostaglandin E2) in definite cytoprotective but minimal antisecretory dose was evaluated in the treatment of duodenal ulcer. One hundred five patients with endoscopically proven duodenal ulcer were randomized in a double-blind manner to receive four times daily either arbacet 25 μg or placebo. Ulcer healing was assessed endoscopically after two and four weeks of treatment. The mean age, sex distribution, and tobacco and alcohol consumption were similar in the two treatment groups. The ulcers of 16 patients in both the placebo and the arbacet-treated group healed after 14 days of treatment. At the end of the study, healing of the ulcer was observed in 69.2% of the arbacet-treated patients and in 60.4% of patients in the placebo treated group. (Difference was not statistically significant). We conclude that cytoprotective doses of arbacet with minimal antisecretory properties are not effective in duodenal ulcer healing.
    Type of Medium: Electronic Resource
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