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  • Lower uterine segment  (2)
  • animal model  (2)
  • Binding isotherms  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Examination of previous caesarean section scars by ultrasound (1988)
    Springer
    Archives of gynecology and obstetrics 243 (1988), S. 221-224 
    Details
    ISSN: 1432-0711
    Keywords: Vaginal delivery ; Caesarean section ; Previous caesarean section scar ; Ultrasonography ; Lower uterine segment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We examined 84 lower segment caesarean section scars by ultrasonography near term. Seventy scars showed good healing with a thickness of the lower uterine segment of more than 3 mm; 14 scars showed poor healing with a thickness of less than 2 mm and loss of continuity. Among 70 patients with good healing, 24 patients delivered vaginally but the remaining 46 patients have had repeat caesarean sections for other obstetric indications. Intraoperative findings in these 46 patients were as follows: Grade I (no thinning of the lower uterine segment), 42; Grade II (thinning and loss of continuity of the lower uterine segment but fetal hair not visible), 4; Grade III (thinning of the lower uterine segment and fetal hair visible), 0. Fourteen patients with poor healing had repeat caesarean sections. Intraoperative findings in these 14 patients were as follows: Grade I, 0; Grade II, 9; Grade III, 5. These results indicate that ultrasound examination detect thinning of the lower uterine segment and may help to determine management.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932271
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity (1995)
    Springer
    Diabetologia 38 (1995), S. 503-508 
    Details
    ISSN: 1432-0428
    Keywords: NSY mouse ; non-insulin-dependent diabetes mellitus ; animal model ; insulin secretion ; isolated islets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The NSY (Nagoya-Shibata-Yasuda) mouse was established as an inbred strain of mouse with spontaneous development of diabetes mellitus, by selective breeding for glucose intolerance from outbred Jcl∶ICR mice. NSY mice spontaneously develop diabetes mellitus in an age-dependent manner. The cumulative incidence of diabetes is 98% in males and 31% in females at 48 weeks of age. Neither severe obesity nor extreme hyperinsulinaemia is observed at any age in these mice. Glucose-stimulated insulin secretion was markedly impaired in NSY mice after 24 weeks of age. In contrast, fasting plasma insulin level was higher in male NSY mice than that in male C3H/He mice (545±73 vs 350±40 pmol/l, p〈0.05, at 36 weeks of age). Pancreatic insulin content was higher in male NSY mice than that in male C3H/He mice (76±8 vs 52±5 ng/mg wet weight, p〈0.05, at 36 weeks of age). Morphologically, no abnormal findings, such as hypertrophy or inflammatory changes in the pancreatic islets, were observed in NSY mice at any age. These data suggest that functional changes of insulin secretion in response to glucose from pancreatic beta cells may contribute to the development of non-insulin-dependent diabetes mellitus (NIDDM) in the NSY mouse. Although insulin sensitivity was not measured, fasting hyperinsulinaemia in NSY mice suggests that insulin resistance may also contribute to the pathogenesis of NIDDM. Since these findings are similar to the pathophysiologic features of human NIDDM patients, the NSY mouse is considered to be useful for investigating the pathogenesis and genetic predisposition to NIDDM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400717
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity (1995)
    Springer
    Diabetologia 38 (1995), S. 503-508 
    Details
    ISSN: 1432-0428
    Keywords: Key words NSY mouse ; non-insulin-dependent diabetes mellitus ; animal model ; insulin secretion ; isolated islets.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The NSY (Nagoya-Shibata-Yasuda) mouse was established as an inbred strain of mouse with spontaneous development of diabetes mellitus, by selective breeding for glucose intolerance from outbred Jcl:ICR mice. NSY mice spontaneously develop diabetes mellitus in an age-dependent manner. The cumulative incidence of diabetes is 98 % in males and 31 % in females at 48 weeks of age. Neither severe obesity nor extreme hyperinsulinaemia is observed at any age in these mice. Glucose-stimulated insulin secretion was markedly impaired in NSY mice after 24 weeks of age. In contrast, fasting plasma insulin level was higher in male NSY mice than that in male C3H/He mice (545 ± 73 vs 350 ± 40 pmol/l, p 〈 0.05, at 36 weeks of age). Pancreatic insulin content was higher in male NSY mice than that in male C3H/He mice (76 ± 8 vs 52 ± 5 ng/mg wet weight, p 〈 0.05, at 36 weeks of age). Morphologically, no abnormal findings, such as hypertrophy or inflammatory changes in the pancreatic islets, were observed in NSY mice at any age. These data suggest that functional changes of insulin secretion in response to glucose from pancreatic beta cells may contribute to the development of non-insulin-dependent diabetes mellitus (NIDDM) in the NSY mouse. Although insulin sensitivity was not measured, fasting hyperinsulinaemia in NSY mice suggests that insulin resistance may also contribute to the pathogenesis of NIDDM. Since these findings are similar to the pathophysiologic features of human NIDDM patients, the NSY mouse is considered to be useful for investigating the pathogenesis and genetic predisposition to NIDDM. [Diabetologia (1995) 38: 503–508]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400717
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Ultrasound examination of caesarean section scars during pregnancy (1991)
    Springer
    Archives of gynecology and obstetrics 248 (1991), S. 129-138 
    Details
    ISSN: 1432-0711
    Keywords: Ultrasound ; Caesarean section scar ; Conventional method ; New method ; Lower uterine segment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two hundred and sixteen transverse caesarean section scars were examined sonographically near term by a conventional method (175 scars) and a new method (41 scars). The new method consisted of obtaining a transabdominal longitudinal scan by the conventional method and also by a 3M conductor, a transabdominal frontal scan to give a surface view of the scar, and transperineal and transvaginal longitudinal scans. The new method was used from 16 weeks of gestation onwards. Of 41 scars scanned by the new method, 31 showed good healing, being more than 2 mm in thickness throughout; 10 scars showed poor healing with a thickness of less than 2 mm and loss of continuity. Of 31 patients with good healing, 8 delivered vaginally and the remaining 23 patients had repeat caesarean sections for other obstetric indications. All patients with ultrasound evidence of poor healing had repeat caesarean sections. At operation the thickness of the lower uterine segment was measured with ophthalmic calipers. There were 4 false negative results (4/83: 4.8%) and 1 false positive result (1/43: 2.3%) with conventional ultrasound and no false positives or false negatives with the new method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02390090
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Binding characteristics of ionic surfactants with human hair (1986)
    Springer
    Colloid & polymer science 264 (1986), S. 798-802 
    Details
    ISSN: 1435-1536
    Keywords: Binding isotherms ; ionic surfactants ; human hair ; thermodynamic parameReferences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Binding isotherms of two types of ionic surfactants, CmH2m +1SO4Na (m = 8,10,12) and CnH2n + 1N+(CH3)3C1 (n=10, 12), to human hair in aqueous solutions were examined to clarify effects of hydrophobic and electrostatic interaction of ionic surfactants with hair. The binding isotherms of anionic surfactants showed cooperativity with discontinuously increasing shapes, while the binding isotherms of cationic surfactants showed a Langmuir-type, regardless of the difference of a hair condition. The calculated free energy change (— ΔG@#@) for binding, obtained from Klotz' plots, suggests that the binding processes are governed mainly by a hydrophobic interaction, and bound surfactants probably expose their alkyl chains to the aqueous phase, since no-ΔG was observed with the increase of m or n and values of enthalpy change(ΔH) were positive or zero.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01500756
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    Paper (German National Licenses)
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