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Observations on synaptic patterns in the dorsal lateral geniculate nucleus of the cat: The C laminae and the perikaryal synapses (1971)

Guillery, R. W. ; Scott, G. L.

Springer

Experimental brain research 12 (1971), S. 184-203

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ISSN: 1432-1106

Keywords: Lateral geniculate ; Cat ; Synapse

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The laminae near the optic tract which have previously been described as C, C1 and C2, have been studied electron microscopically and compared ] to the A laminae. In the A laminae most of the presumed retinogeniculate axons end in encapsulated synaptic zones that contain multiple interconnected synaptic profiles. Only a few of these axons form simple axodendritic synapses upon proximal dendritic segments of the largest cells. In the C laminae the situation is reversed. Most of the retinogeniculate axons end as simple synapses upon medium or small dendrites and few end in encapsulated synaptic zones. Further, these zones are simpler in the C laminae than in the A laminae. The neuronal profiles are smallest and the synaptic interconnections appear to be least complex in lamina C2, where there are only a few, small, presumed retinogeniculate terminals. Of the three C laminae, lamina C, furthest from the optic tract, shows the largest profiles and the most complex interconnections. Bundles of very fine axons occur in all the laminae, but they dominate the regions closest to the optic tract (lamina C2) where they tend to run parallel to the lamina. Some of the largest cells in laminae A, A1 and C are contacted by very fine perisomatic axons which contain round vesicles. These axons have not been described before and are likely to represent an input too fine to have been demonstrable by light microscopical methods.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00234315

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Comparison of computational methods applied to oxazole, thiazole, and other heterocyclic compounds (1993)

Shaffer, Alan A. ; Wierschke, Scott G.

New York, NY [u.a.] : Wiley-Blackwell

Journal of Computational Chemistry 14 (1993), S. 75-88

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ISSN: 0192-8651

Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Computer Science

Notes: A variety of computational methods, including the semiempirical techniques AM1, PM3, and MNDO, and the thermochemical basis sets of Benson and Stine, was used to calculate and compare heats of formation (ΔHf°) data for optimized geometries of a variety of aromatic and nonaromatic heterocycles. Detailed analyses, including 6-31G* and MP2/6-31G* ab initio calculations, were performed for the oxazole and thiazole heterocycles. The results indicate a scatter among the methods sensitive to the nature of the heterocycle. This was in particular evident in the oxazole molecule, where AM1 gave a singularly high value of ΔHf° consistent with longer calculated bond lengths, particularly about the oxygen atom. Aromatic stabilization energy appears to be addressed differently among the employed methods. Implications of this contrast applied to calculation of macromolecular systems containing heterocyclic units are discussed.

Additional Material: 10 Ill.