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  • Biomechanics  (1)
  • Cardiolipin Antibodies  (1)
  • Catecholamines  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of b-adrenoceptor-blockade on stress-induced adrenocorticotrophin release in humans (1998)
    Springer
    European journal of applied physiology 77 (1998), S. 523-526 
    Details
    ISSN: 1439-6327
    Keywords: Key words Adrenocorticotrophin ; Cortisol ; Catecholamines ; Propranolol ; Stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated the mechanisms of stress-induced alterations in adrenocorticotrophin (ACTH) release. Tandem parachutists received either a placebo or the β-adrenoceptor antagonist propranolol prior to a first time parachute jump. Blood samples were drawn 4 h before, immediately after, and 1 h after the jump. Cortisol and catecholamine concentrations displayed a significant stress-induced increase in both groups. The ACTH plasma concentrations significantly increased in the placebo and the propranolol group, with significantly more pronounced changes in the propranolol-treated subjects compared to the placebo group. These data demonstrated a stress-induced increase of ACTH plasma concentrations in humans that was enhanced by β-blockade.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004210050370
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Antibodies to cardiolipin and intermediate filaments: A study of autoimmunity in rheumatoid arthritis (1990)
    Springer
    Clinical rheumatology 9 (1990), S. 509-516 
    Details
    ISSN: 1434-9949
    Keywords: Rheumatoid Arthritis ; Cardiolipin Antibodies ; Intermediate Filament Antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Autoantibodies to cardiolipin and intermediate filaments have both been reported with increased frequency in rheumatoid arthritis. We evaluated the frequency, pathological significance, and diagnostic relevance of these autoantibodies in a series of 124 patients and controls. We studied 81 patients with rheumatoid arthritis, 23 with osteoarthritis, and 20 normals. Antibodies to cardiolipin were measured by an ELISA method and antibodies to intermediate filaments were measured by indirect immunofluorescence using HEp2 cells. Antibodies to cardiolipin were present in 58% of rheumatoid patients and antibodies to intermediate filaments were present in 55% rheumatoid patients. They were both predominantly of IgM class, and were more frequent than in normal or osteoarthritic controls. Correlating levels of both these auto-antibodies to clinical and laboratory measures of disease activity such as Ritchie articular index and C-reactive protein level showed that no consistent relationships existed. They were not related to other auto-antibodies such as rheumatoid factors and antinuclear antibodies, nor to each other. These results show that antibodies to cardiolipin and intermediate filaments in rheumatoid arthritis are of no diagnostic value, they are not related to disease activity, and have no relationship to other autoimmune disturbances. We suggest that several pathological mechanisms must be involved in the development of auto-antibodies in rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02030513
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Biomechanical analyses of some instrumentations for stabilisation of dorso-lumbar spinal injuries (1983)
    Springer
    Medical & biological engineering & computing 21 (1983), S. 494-502 
    Details
    ISSN: 1741-0444
    Keywords: Biomechanics ; Fixation device ; Spinal fracture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Quantitative biomechanical analyses of approaches for the reduction and fixation of lumbardorsal injury are presented in this paper, entailing (i) classification of the types of injuries, (ii) analysis of the critical functional levels of forces exerted on the injured spinal structures and the stabilisation devices and (iii) the basis for the various modalities of injury reduction stabilisation modes, and for the use of conventional posteriorly attached compression or distraction devices, as well as anteriorly placed vertebral stabilisation-fixation device.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442639
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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