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  • 1
    ISSN: 1432-2013
    Keywords: Expansion of Intrathoracic Vascular Volume ; Water and Electrolyte Balance ; Immersion Diuresis ; Blood Volume Control ; Extracellular Fluid Distribution ; Simulierte Hypervolaemie ; Wasser- und Elektrolythaushalt ; Immersionsdiurese ; Blutvolumenregulation ; Extracellulare Flüssigkeitsverteilung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intrathoracic blood volume was increased by prolonged immersion in thermo-indifferent (34δ C) water. Urinary excretion patterns of free water and electrolytes during immersion were compared with those for an identical period of the previous day when the subjects were performing routine activity. Plasma volume changes during immersion were compared with the concomitant urine volume which under these conditions can be equated with total fluid loss. The nature of the immersion diuresis depended on the state of hydration. Normally hydrated subjects showed a rise in free water clearance whereas a hydropenic group increased urine volume by an augmentation of osmolar clearance. Sodium excretion during immersion rose from 118±48 (SD) to 180±51.7 (SD) μeq./h×kg in normally hydrated subjects (p〉0.05) and from 66.8±22.5 (SD) to 152±43.3 (SD) μeq./h×kg (p〈0.01) in the hydropenic group. Immersion led to plasma volume reduction in all cases. Plasma volume reduction constituted a much greater percentage of the urine volume in hydropenic subjects (98.8±35.4 (SD)%) than in the normally hydrated ones (19.3±8.56 (SD)%). It is concluded that engorgement of the intrathoracic volume-sensitive vascular areas may not only lead to increased fluid elimination by the kidney but at the same time to a shift of fluid from plasma into the interstitial space. Both effects serve the homeostatic control of blood volume.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Venous Tone ; Transmural Central Venous Pressure ; Immersion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Peripheral venous tone, central venous and oesophageal pressures were recorded while the upright sitting subjects were immersed to the neck in a thermoneutral water bath. The central venous pressure rose from 3.4 to 15.2 mm Hg and the oesophageal pressure from −0.4 to +3.4 mm Hg. The transmural pressure, which determines the enddiastolic volume of the heart, increased by 8.0 mm Hg. Plethysmographic determinations of peripheral venous tone revealed a relaxation of the peripheral veins: after a quick initial decrease of the volume elasticity coefficient (E′15) from 16.6 to 13.5 mm Hg/ml/100 g tissue there is a continuous decline to 11.8 mm Hg/ml/100 g tissue after 3 hrs immersion. This relaxation persists for at least 1 hr after termination of immersion.
    Type of Medium: Electronic Resource
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