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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 35 (1993), S. 459-460 
    ISSN: 1432-1920
    Keywords: Cauda equina syndrome ; Magnetic resonance imaging ; Paraganglioma ; Spinal tumour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the clinical and imaging features of a paraganglioma of the cauda equina. Raised CSF protein caused an unusual appearance of the spinal canal below the obstruction. No specific identifying features were encountered; paraganglioma is uncommon in this site and usually thought to be an ependymoma or a neuroma; histopathological examination is necessary for correct diagnosis.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-0350
    Keywords: Hydrocephalus ; Leukemia ; Leukoencephalopathy ; Magnetic resonance imaging ; Shunt surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation. The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate. Both patients underwent cerebrospinal fluid shunting mainly for their hydrocephalus. The imaging studies have shown that both hydrocephalus and leukoencephalopathy have improved significantly after ventriculoperitoneal shunt insertion. We review the pathophysiology of prophylaxis-related encephalopathy in leukemia patients and summarize its clinical, histological, and radiological characteristics. We also discuss the possible contribution of altered cerebrospinal fluid dynamics in the development of leukoencephalopathy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 5 (1987), S. 548-561 
    ISSN: 0736-0266
    Keywords: Acetabulum ; Total hip replacement ; Loosening ; Bone stresses ; Implant interface ; Porous ingrowth ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Two-dimensional linear and contact finite element analyses were conducted of total hip arthroplasty using metal-backed, porous ingrowth acetabular components. The stress transmission characteristics from the component to the surrounding bone were given special attention. Resultant loads of 20 and 40° medial of vertical were studied, and the influence of adding a metal flange to the rim of the cup was evaluated. The results indicated that when a conventional metal-backed component (without a flange) is initially implanted and subjected to normal loading, these components may experience distraction between the component and the surrounding bone at inferior sites. Compressive stresses in the superior dome cancellous bone, however, will be substantial. If complete porous ingrowth is achieved, the superior dome compressive stresses will be reduced and substantial shear stresses created. In addition, high local bone stresses were found at the component rim. If bone ingrowth is achieved only in specific locations, stress transmission will be dictated by those locations and may differ markedly from the case of complete bone ingrowth. In the event that no porous ingrowth is achieved and a fibrous layer forms around the component, the interface stresses will be similar to those calculated for the natural hip. The addition of a flange to the rim of the cup will reduce the magnitude of the radial stresses transmitted to the cancellous bone superiorly and medially by directly transferring some of the load to the lateral wall of the pelvis. The flange will also help to relieve the high local stresses that are found at the component rim.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 3 (1985), S. 435-446 
    ISSN: 0736-0266
    Keywords: Acetabulum ; Hip joint ; Pressure distribution ; Contact stresses ; Bone stresses ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Two-dimensional finite element analyses were conducted of the normal hip using contact elements at the joint surface. The models studied were constructed for a slice through the pubis, acetabulum, and ilium. In the analyses the proximal femur was pressed into the acetabulum and intraarticular pressures and principal stresses in the joint region were determined for different load magnitudes and directions and various boundary conditions. Three sets of boundary conditions were examined: (a) deformable pubic symphysis, (b) rigid pubic symphysis, and (c) simulations of experimental studies. In the deformable model the pubic symphysis was free to displace in the sagittal plane and rotate. In the rigid model the pubic symphysis was rigidly fixed. Superoposterior loading resulted in high-contact pressures at the acetabular dome for all sets of boundary conditions. For the deformable model subject to a more medially directed load the acetabulum closed in such a manner as to squeeze the head of the femur creating high-contact pressures superiorly and inferiorly. This resulted in significant compressive stresses in the superior dome cancellous bone and inferior cancellous bone. The cumulative effect of this squeezing action with normal biological remodeling may cause elongation of the femoral head resulting in asphericity and incongruity of the unloaded hip joint articular surfaces. Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model. Finite element simulations of previous experimental studies modeled the close proximity of the fixation to the fixation to the excised acetablulum. These boundary conditions prevented the squeezing caused by pelvis deformations. The resulting contact areas, pressure distributions, and bone stresses were very different from those of more anatomic, deformable pubic symphysis model. These findings demonstrate the sensitivity of hip contact pressures and stresses to imposed boundary conditions and indicate that care should be taken to simulate anatomic conditions in experimental and theoretical studies.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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