ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Ion-pair separation
;
Salt concentration
;
Charge number of solute
;
Gouy-Chapman theory
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Thermodynamic and numerical treatments have been combined with Gouy-Chapman theory were to show that the effect of the salt concentration on the capacity factor in reversed-phase ion-pair liquid chromatography (RP-IPC) can be expressed as lnk′=A+blnCs. The parameter B is related to the charge number of the solute, and the parameter A is determined by both electrostatic and nonelectrostatic interaction, and can the linearly correlated with logarithm of the capacity factor in RP-HPLC for the solute with one negative charge. It also been observed that the electrostatic interaction is reduced with increasing salt concentration in RP-IPC, and this effect is more remarkable for solutes with more than the one negative charge of sulphonic acids.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02327899
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