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  • 1
    Electronic Resource
    Electronic Resource
    Idiopathic prolactin cell hyperplasia of the pituitary mimicking prolactin cell adenoma: a morphological study including immunocytochemistry, electron microscopy, and in situ hybridization (1991)
    Springer
    Acta neuropathologica 82 (1991), S. 147-151 
    Details
    ISSN: 1432-0533
    Keywords: Hyperplasia ; Pituitary ; Pathology ; Prolactin ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Prolactin cell adenoma is the most frequently found lesion in surgically removed pituitaries of patients with hyperprolactinemia. However, in several instances, instead of prolactin cell adenoma, other lesions are encountered by morphological investigation. We report here the morphological findings in a patient with hyperprolactinemia who underwent transsphenoidal pituitary surgery for suspected prolactin cell adenoma. A morphological diagnosis of tumor could not be confirmed and massive diffuse prolactin cell hyperplasia was identified. The aim of this publication is to describe the lesion by histology, immunocytochemistry, electron microscopy, and in situ hybridization and to call attention to primary prolactin cell hyperplasia which can mimic prolactin cell adenoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293958
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prepontine cyst lined by respiratory epithelium with squamous metaplasia: immunohistochemical and ultrastructural study (1992)
    Springer
    Acta neuropathologica 83 (1992), S. 564-568 
    Details
    ISSN: 1432-0533
    Keywords: Brain ; Cyst ; Respiratory epithelium ; Metaplasia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An 8.5-year-old female presented with multiple episodes of aseptic meningitis and was found to have a cystic lesion in the prepontine region. Microscopic examination revealed a respiratory-type epithelium with squamous metaplasia. Like its normal analogue in the respiratory tract, the epithelium of these intracranial cysts can undergo squamous metaplasia when chronically irritated. The ultrastructural and immunohistochemical characteristics of the transition from ciliated epithelium to squamous metaplasia are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310038
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Intracranial and spinal metastases from a ganglioglioma with unusual cytogenetic abnormalities in a patient with complex partial seizures (1997)
    Springer
    Child's nervous system 13 (1997), S. 550-555 
    Details
    ISSN: 1433-0350
    Keywords: Key words Ganglioglioma ; Cytogenetics ; Metastasis ; Brain neoplasm ; Pathology ; Epilepsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe an unusual clinical presentation of a ganglioglioma in a patient with complex partial seizures. The patient underwent a right temporal lobectomy with subtotal tumor resection at age 15 years, followed by a complete resection 1 year later. Follow-up MRI scan a year later documented recurrence and leptomeningeal dissemination. Another biopsy was performed. Pathological examination revealed similar histology in all three resections, with a ganglioglioma showing no evidence of anaplasia. The tumor exhibited a number of karyotypic abnormalities, notably, a paracentric inversion of chromosome 7. In summary, despite lacking anaplastic features by conventional histological criteria, this ganglioglioma showed an unsusual karyotype and demonstrated radiological evidence of widespread dissemination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003810050136
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Coexistence of hemimegalencephaly and chronic encephalitis Detection of cytomegalovirus by the polymerase chain reaction (1997)
    Springer
    Child's nervous system 13 (1997), S. 35-41 
    Details
    ISSN: 1433-0350
    Keywords: Key words Cytomegalovirus ; Hemimegalencephaly ; Encephalitis ; Epilepsy ; Brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the extraordinary association of hemimegalencephaly with chronic encephalitis and cytomegalovirus (CMV) positivity in a 5-month-old infant with intractable seizures and a left hemisphere resection. Microscopy revealed a severe neuronal migration disorder (NMD) with fusion of gyri, marked disarray of neuronal lamination, neuronal gigantism and extensive neuronal heterotopias. Also widespread were microglial nodules, gliosis and nodular calcifications and some foci of frank necrosis with calcification. Occasional perivascular and leptomentingeal lymphocytic infiltrates were present. No viral inclusions were identifiable. Polymerase chain reaction on multiple specimens showed unequivocal CMV positivity. In intrauterine CMV infection, NMDs such as polymicrogyria are well recognized, but the association of hemimegalencephaly with CMV infection has not previously been described. Our finding of chronic encephalitis with CMV positivity and hemimegalencephaly in the same patient raises questions about the role of CMV in the etiopathogenesis of the NMD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003810050037
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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