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  • Brain death  (1)
  • C3  (1)
  • Cataract  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Modulation of C2 and C3 gene expression of human peripheral blood monocytes by interleukin 1β, interferon γ, tumor necrosis factor α and lipopolysaccharide (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 1148-1150 
    Details
    ISSN: 1420-9071
    Keywords: IL-1β ; IFNγ ; LPS ; C2 ; C3
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of interleukin 1β (IL-1β), interferon γ (IFN-γ), tumor necrosis factor α (TNFα) and lipopolysaccharide (LPS) on the expression of the C2 and C3 genes in human adherent monocytes was studied. Stimulation of monocytes with IFN-γ increased both C2 and C3 mRNA. IL-1β also increased C2 mRNA level, whereas C3 gene expression was not enhanced. TNFα failed to increase either C2 or C3 mRNA. LPS increased C2 mRNA, but suppressed C3 gene expression. These results suggest that C2 and C3 production by monocytes is regulated by IL-1β and IFN-β in the local tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01948011
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Morphological and functional alterations of the hypothalamic-pituitary system in brain death with long term bodily living (1992)
    Springer
    Acta neurochirurgica 115 (1992), S. 31-36 
    Details
    ISSN: 0942-0940
    Keywords: Brain death ; hypothalamic hormone ; hypothalamic-pituitary system ; pituitary-hormones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Hypothalamic hormones as well as anterior pituitary hormones were detected in the peripheral plasma after the diagnosis of brain death. It is possible that residual hypothalamic tissue was functioning after satisfying the usual criteria of total brain death. To examine this possibility, endocrinological and morphological alterations of the hypothalamic-pituitary system was evaluated in 28 brain dead patients. Intrinsic ADH was depleted in the plasma shortly after the diagnosis of brain death. Anterior pituitary hormones were initially detected in all patients, but gradually disappeared. The direct TRH (thyrotropin releasing hormone) stimulation to the anterior lobe was responded to well. Morphological studies showed a partial necrosis of the anterior lobe and the preservation of the posterior lobe for as long as a week. These data prove that the pituitary is partially preserved after brain death. LH-RH (luteinizing hormone releasing hormone) was detected in the peripheral plasma of all patients and GRF (growth hormone releasing factor) was detected in half of the patients for as long as 15 days, but autopsy revealed the fact that the brain tissue including the hypothalamus became extensively necrotic after the sixth day of brain death. In order to solve this controversy it is proposed that these hormones originate from extracranial tissues such as pancreas. The detection of hypothalamic hormones after the diagnosis of brain death therefore is not contradictory to the concept of total brain death.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400587
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    A case of Menkes syndrome with cataracts (1982)
    Springer
    European journal of pediatrics 138 (1982), S. 357-358 
    Details
    ISSN: 1432-1076
    Keywords: Menkes' syndrome ; Cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 2-year and 9-month-old boy with Menkes syndrome is reported. In addition to the typical features of this syndrome our patient had bilateral cataracts. The relation between abnormal copper metabolism and cataract is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442519
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    Paper (German National Licenses)
    Fulltext
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