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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 26 (1976), S. 407-422 
    ISSN: 1432-1106
    Keywords: Climbing fibers ; Inferior olive ; Brain stem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The sources and pathways of the climbing fibers to the cerebellar posterior vermis were studied with combined electrophysiological and anatomical methods in cats. Recording from identified cerebellar Purkinje cells, monosynaptic climbing fiber (CF) responses have been obtained both for stimulation of the inferior olive (IO) and various parts of the brain stem (BS). CF responses were found to be of three types, IO only, BS only or both IO and BS. However the responses to BS stimulation were very few in number in comparison with IO or IO and BS types of responses. The latencies of the responses were shorter for the BS cases consistent with their distance from the cerebellum. A comparison of latencies and the relative responsiveness of the different area of the brain stem which were studied, indicate that part of the CF ascend through the pontine region and enter the cerebellum by way of the medium and superior peduncles. This finding is confirmed by the results of anatomical studies in which degenerating fibers were found in the molecular layer (using the Nauta technique) after lesion of the brachium pontis but not after lesions of the medial portion of the pons. Similarly, injection of radioactive leucine into the pontine nuclei failed to show any labeled fibers in the molecular layer. Horseradish peroxidase (HRP) was injected into localized regions of the posterior vermis after total bilateral destruction of the inferior peduncles. Large numbers of positive, marked cells were still found in the inferior olive. It is concluded that nearly all, if not all, the climbing fibers originate in the inferior olive and that they ascend to the cerebellum by way of all the peduncles.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Requirements engineering 1 (1996), S. 47-62 
    ISSN: 1432-010X
    Keywords: Conceptual schema analysis ; Information system re-engineering ; Reference components ; Similarity measures ; Schema clustering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The paper deals with the problem of building an inventory of information systems for the public administration, with reference to an ongoing project in Italy. We describe the investigation techniques defined for collecting information and the techniques developed for a systematic analysis of the large set of conceptual schemas resulting from the investigation. These schemas describe the data used by the public administration work processes. In particular, we describe the conceptual schema of the inventory, which is the basis for discussing the methodology of investigation, the choice of units of investigation, the data collection and merging, and the access to information. Then, we present the schema analysis techniques developed to analyse semi-automatically the large set of conceptual schemas resulting from the investigation. In particular, we illustrate indexing techniques for identifying representative descriptors of schemas and similarity techniques to compare schemas for their classification into families. Finally, the tool developed to support the storage, analysis and classification of schemas is described and experimentation results are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 42 (1981), S. 383-391 
    ISSN: 1432-1106
    Keywords: Harmaline ; Tremor ; Interposito ; Rubral system ; Oculomotricity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Units were recorded extracellulary in the cat brainstem under the effect of tremogenic doses of harmaline. They were localized post mortem and the units discharging at the harmaline tremor frequency were mapped. Harmaline-sensitive neurons were found in the bulbo-pontine reticular formation, in particular, in the lateral reticular nucleus and the nucleus reticularis tegmenti pontis. The nucleus interpositus as well as the red nucleus also displayed numerous units discharging at the tremor frequency, indicating that the cerebello-interposito-rubro-spinal system controlling the flexor muscles participate in harmaline tremor. Participation of the oculomotor system in the harmaline-induced tremor was tested at the level of the vestibular neurons relaying the vestibulo-ocular reflex, the motoneurons, the eye muscles and the eye movements. No rhythmic discharge at the tremor frequency nor eye movements could be detected, indicating that harmaline tremor does not affect the oculomotor system.
    Type of Medium: Electronic Resource
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