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1

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A double blind trial of UK-38,485, an orally active thromboxane synthetase inhibitor, in the treatment of Raynaud's syndrome (1984)

Rustin, M. H. A. ; Grimes, S. M. ; Kovacs, I. B. ; [et al.]

Springer

European journal of clinical pharmacology 27 (1984), S. 61-65

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ISSN: 1432-1041

Keywords: thromboxane synthetase inhibitors ; Raynaud's syndrome ; systemic sclerosis ; UK-38,485 ; ischaemic attacks ; red blood cell rheology

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Ten patients with moderate to severe Raynaud's syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration of ischaemic attacks, the mean hand temperatures, forearm and digital blood flow and red blood cell rheology.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00553156

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2

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A double blind trial of UK-38,485, an orally active thromboxane synthetase inhibitor, in the treatment of Raynaud’s syndrome (1984)

Rustin, M. H. A. ; Grimes, S. M. ; Kovacs, I. B. ; [et al.]

Springer

European journal of clinical pharmacology 27 (1984), S. 61-65

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ISSN: 1432-1041

Keywords: thromboxane synthetase inhibitors ; Raynaud’s syndrome ; systemic sclerosis ; UK-38,485 ; ischaemic attacks ; red blood cell rheology

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Ten patients with moderate to severe Raynaud’s syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration of ischaemic attacks, the mean hand temperatures, forearm and digital blood flow and red blood cell rheology.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02395208

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3

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Some rotifers from coastal lakes of Brazil, with description of a new rotifer, Lepadella (Xenolepadella) curvicaudata n. sp. (1990)

Turner, P. N.

Springer

Hydrobiologia 208 (1990), S. 141-152

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ISSN: 1573-5117

Keywords: rotifers ; Brazil ; coastal lakes ; neotropical ; distribution

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Abstract Four relatively rare, two common rotifers and one rotifer new to science are described from some coastal lakes near Rio de Janeiro, Brazil. Each rotifer is described in detail, and several are accompanied by illustrations and mensuration data. Geographic distribution and individual habitats of the rotifers are also discussed. Several species show a larger geographic distribution than previously known.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00007780

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4

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A new rotifer from a coastal lake in Southeastern Brazil: Hexarthra longicornicula n. sp. (1987)

Turner, P. N.

Springer

Hydrobiologia 153 (1987), S. 169-174

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ISSN: 1573-5117

Keywords: rotifers ; taxonomy ; new species ; Neotropis ; Brazil

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Abstract A new rotifer is described from among samples taken from coastal lakes in southeastern Brazil. Comparisons to related rotifers are made. This new animal belongs to the Hexarthra mira-intermedia species group by way of its general morphological configuration, the number of teeth in the trophi (5), and the two club-shaped caudal appendages (CSCA's). An extremely long dorsal antenna and very long setae extending from the bend in the ventro-lateral arm characterize this animal's speciation.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00006648

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5

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Direct-prediction quasi-Newton methods in Hilbert space with applications to control problems (1977)

Turner, P. R. ; Huntley, E.

Springer

Journal of optimization theory and applications 21 (1977), S. 199-211

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ISSN: 1573-2878

Keywords: Variable-metric methods ; optimization theorems ; Hilbert spaces ; control theory

Source: Springer Online Journal Archives 1860-2000

Topics: Mathematics

Notes: Abstract In this paper, the Hilbert-space analogue of a result of Huang, that all the methods in the Huang class generate the same sequence of points when applied to a quadratic functional with exact linear searches, is established. The convergence of a class of direct prediction methods based on some work of Dixon is then proved, and these methods are then applied to some control problems. Their performance is found to be comparable with methods involving exact linear searches.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00932520

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6

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Direct prediction methods in Hilbert space with applications to control problems (1977)

Huntley, E. ; Turner, P. R.

Springer

Journal of optimization theory and applications 22 (1977), S. 399-415

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ISSN: 1573-2878

Keywords: Variable-metric methods ; optimization theorems ; Hilbert spaces ; control theory

Source: Springer Online Journal Archives 1860-2000

Topics: Mathematics

Notes: Abstract In this paper, the convergence of variable-metric methods without line searches (direct prediction methods) applied to quadratic functionals on a Hilbert space is established. The methods are then applied to certain control problems with both free endpoints and fixed endpoints. Computational results are reported and compared with earlier results. The methods discussed here are found to compare favorably with earlier methods involving line searches and with other direct prediction quasi-Newton methods.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00932863

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7

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Variable metric methods in Hilbert space with applications to control problems (1976)

Turner, P. R. ; Huntley, E.

Springer

Journal of optimization theory and applications 19 (1976), S. 381-400

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ISSN: 1573-2878

Keywords: Variable metric methods ; optimization theorems ; Hilbert spaces ; control theory

Source: Springer Online Journal Archives 1860-2000

Topics: Mathematics

Notes: Abstract This paper is concerned with some of the most powerful methods of minimizing functionals on Hilbert space. It is established that certain classes of these methods are equivalent and their convergence is proved for certain nonquadratic functionals on a Hilbert space. A computational study of these methods applied to a control problem is also included with particular reference to the equivalence of methods mentioned above.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00941483

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