ISSN:
1432-2072
Keywords:
Bromocriptine
;
Dopamine
;
Schizophrenia
;
Autoreceptor
;
Prolactin
;
Growth hormone
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Bromocriptine (0.5–6.0 mg/day) was administered to seven unmedicated chronic schizophrenic and two schizoaffective patients. Transient slight improvement was noted in four patients and marked improvement in one other. Clinical improvement was associated with nausea and drowsiness. These doses of bromocriptine stimulated serum growth hormone and inhibited serum prolactin levels in some subjects. These results suggest that bromocriptine may stimulate dopamine autoreceptors and, through this mechanism, attenuate symptoms in a small proportion of psychiatric patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00439271
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