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  • Cell & Developmental Biology  (18)
  • Metabolism  (3)
  • CCAATT enhancer binding protein  (2)
  • 1
    Electronic Resource
    Electronic Resource
    A simple model for alanine metabolism in isolated rat hepatocytes
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 1175 (1993), S. 161-173 
    Details
    ISSN: 0167-4889
    Keywords: Alanine ; Hepatocyte ; Metabolism ; Model
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4889(93)90019-L
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Glycine, a new regulator of glutamine metabolism in isolated rat-liver cells
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 1175 (1992), S. 13-20 
    Details
    ISSN: 0167-4889
    Keywords: (Rat hepatocyte) ; Glutamine ; Glycine ; Metabolism
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4889(92)90004-U
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  • 3
    Electronic Resource
    Electronic Resource
    Transcription, adipocyte differentiation, and obesity (1996)
    Springer
    Journal of molecular medicine 74 (1996), S. 347-352 
    Details
    ISSN: 1432-1440
    Keywords: Adipocytes ; CCAATT enhancer binding protein ; Gene expression ; Nuclear receptors ; Peroxisome proliferator activated receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Differentiation of adipogenic precursor cells into mature adipocytes is a complex phenomenon, characterized by an ordered expression of adipocyte-specific genes, triggered by a set of interacting transcription factors. The most important transcription factors involved in this process are the γ form of peroxisome proliferator activated receptors (PPARγ) and the various members of the CCAAT enhancer binding proteins (α, β, and δ). In addition to PPARγ and these enhancer binding proteins, several other transcription factors, including ADD-1 (SRE-BP), HMGI-C, are involved in regulating this process. Altered activity and/or expression of these transcription factors, will induce the expression of target genes in the differentiating cells, ultimately resulting in the phenotypical characteristics of the adipocytes. It is speculated that modulation of these transcription factors by either pharmacological or dietary manipulations might influence adipocyte differentiation and prove beneficial in the prevention and treatment of obesity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210629
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  • 4
    Electronic Resource
    Electronic Resource
    Transcription, adipocyte differentiation, and obesity (1996)
    Springer
    Journal of molecular medicine 74 (1996), S. 347-352 
    Details
    ISSN: 1432-1440
    Keywords: Key words Adipocytes ; CCAATT enhancer binding protein ; Gene expression ; Nuclear receptors ; Peroxisome proliferator activated receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Differentiation of adipogenic precursor cells into mature adipocytes is a complex phenomenon, characterized by an ordered expression of adipocyte-specific genes, triggered by a set of interacting transcription factors. The most important transcription factors involved in this process are the γ form of peroxisome proliferator activated receptors (PPARγ) and the various members of the CCAAT enhancer binding proteins (α, β, and δ). In addition to PPARγ and these enhancer binding proteins, several other transcription factors, including ADD-1 (SRE-BP), HMGI-C, are involved in regulating this process. Altered activity and/or expression of these transcription factors, will induce the expression of target genes in the differentiating cells, ultimately resulting in the phenotypical characteristics of the adipocytes. It is speculated that modulation of these transcription factors by either pharmacological or dietary manipulations might influence adipocyte differentiation and prove beneficial in the prevention and treatment of obesity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001090050036
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    The end products of the metabolism of aromatic amino acids by clostridia (1976)
    Springer
    Archives of microbiology 107 (1976), S. 283-288 
    Details
    ISSN: 1432-072X
    Keywords: Clostridia ; Phenylalanine ; Tyrosine ; Tryptophan ; Metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The end products of the metabolism of phenylalanine, tyrosine and tryptophan by growing cultures of clostridia have been identified. The species used were Clostridium aminovalericum; C. bifermentans; C. botulinum proteolytic type A; C. botulinum proteolytic type B; C. cochlearium; C. difficile; C. ghoni; C. histolyticum; C. lentoputrescens; C. limosum; C. lituseburense; C. malenomenatum; C. mangenoti; C. propionicum; C. putrefaciens; C. sordellii; C. sporogenes; C. sporosphaeroides; C. sticklandii; C. subterminale; C. tetani; C. tetanomorphum. The mixture of aromatic compounds formed, which depended upon the species, included phenyl acetic acid, phenyl propionic acid, phenyl lactic acid, phenol, p-cresol, p-hydroxy phenyl acetic acid, p-hydroxy phenyl propionic acid, indole, indole acetic acid and indole propionic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00425340
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  • 6
    Electronic Resource
    Electronic Resource
    Choroid plexus and paraphysis in lower vertebratesSupported in part by Public Health Service grant NB-5383 from the National Institute of Neurological Diseases and Blindness. (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 120 (1966), S. 157-187 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cytoarchitecture of the choroid plexus of the third ventricle and the paraphysis was investigated in some lower vertebrates to compare the histologic characteristics of these organs. Both epithelia are similar in appearance in the same class. Minor microscopic variations exist in the different classes of vertebrates, but do not provide a fundamental distinction between the two organs. The epithelia, moreover, have similar staining properties, contain mucicarmine- and PAS-reactive materials, and are derived from a common neuroepithelium. Tubules are identified in the choroid plexus and in the paraphysis; all are similarly formed by simple folding of epithelium on the surface into the stroma. The paraphyses in all vertebrates studied contain villi similar to those seen in the choroid plexus. Cilia are identified in both choroidal and paraphyseal epithelia, and are not an indication of degree of epithelial differentiation. Many types of epithelium are noted in both organs during histologic differentiation as well as in the mature stage. Functionally, the choroid plexus is active in both secretion and absorption. Accumulation of particulate material within the epithelial cytoplasm may indicate phagocytic as well as absorptive activity of cells. Based on a common neuroepithelial origin and similar histochemical properties, we conclude that the paraphysis is a modified choroid plexus. The velum transversum is an arbitrary boundary between diencephalon and telencephalon, and is itself formed of choroid plexus. The medial telencephalic ventricle is the rostral portion of the third ventricle. All neuroepithelial infoldings at the rostral end of the diencephalic roof including the velum transversum are intraventricular choroid plexuses; the neuroepithelial outpouchings in this region are the extraventricular choroid plexuses (paraphysis) of the diencephalon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051200204
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  • 7
    Electronic Resource
    Electronic Resource
    Binding of antibodies in liposomes to extracellular matrix antigens (1985)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 28 (1985), S. 23-29 
    Details
    ISSN: 0730-2312
    Keywords: fibronectin ; laminin ; liposomes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: We have incorporated antibodies against fibronectin or laminin into liposomes and studied their interaction with insoluble forms of these antigens. The antibodies, after modification by palmitoylchloride, were incorporated into the lipid bilayer by the cholate dialysis method. The antibodies in the liposomes recognized their specific antigen with little reaction to the alternative attachment protein or to albumin (〈2%). The binding of antibody-containing liposomes to insoluble antigen was inhibited by soluble antibodies to the respective antigens but not by antibodies to other antigens. The affinity constant of the liposome-antibody complex with the antigen was estimated at 1-10 × 10-9 M liposomes. Thus, antibodies in liposomes retain their reactivity and specificity, and the reaction constant is comparable to that observed for immune complexes.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240280105
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  • 8
    Electronic Resource
    Electronic Resource
    Ipsilaterally projecting rubrospinal neurons in adult and developing opossums (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 231 (1991), S. 538-547 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: We have combined injections of Fast Blue with lesions of the rubrospinal tract rostral and contralateral to them to determine if an ipsilateral rubrospinal projection exists in adult or developing opossums and, if so, to characterize the neurons giving rise to it. Although the results indicate that some rubral neurons project ipsilaterally, they are very few in number. Using quantitative and image analysis techniques, we have shown that 0.6% of the rubral neurons that project to the lumbar cord in adult opossums do so ipsilaterally and that such neurons are comparable in location and size to those that project contralaterally. Similar results were obtained in developing opossums. Our results are discussed in light of rubrospinal development and ongoing experiments related to rubrospinal plasticity.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092310415
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  • 9
    Electronic Resource
    Electronic Resource
    Intracranial and extracranial circulations in the dog: Anatomic and angiographic studiesThis investigation was supported in part by Research Grant B-1088 from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Public Health Service. (1959)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 105 (1959), S. 343-381 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001050303
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  • 10
    Electronic Resource
    Electronic Resource
    Anatomic and angiographic study of the vertebral-basilar arterial system in the dogThis investigation was supported in part by research grants B-1088 and B-2417 from the National Institutes of Health, Public Health Service. (1962)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 110 (1962), S. 187-197 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001100206
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