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  • 1
    Electronic Resource
    Electronic Resource
    Involvement of capsaicin-sensitive sensory nerves in early and delayed cardioprotection induced by a brief ischaemia of the small intestine (1999)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 359 (1999), S. 243-247 
    Details
    ISSN: 1432-1912
    Keywords: Key words Myocardial infarction ; Preconditioning ; Small intestine ; Capsaicin ; Sensory nerves ; CGRP ; (calcitonin gene-related peptide)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Early cardioprotection can be achieved by a brief ischaemia of noncardiac tissues. Our study examined whether a brief ischaemia of the small intestine induces both early and delayed cardioprotection in the rabbit and assessed the possible mechanism involved in the activation of capsaicin-sensitive sensory nerves. The plasma concentration of creatine kinase (CK) and infarct size (necrotic zone/left ventricular zone) after 30 min coronary artery occlusion and 180 min reperfusion were determined in rabbits. Infarct size was 35.5±6.8% in the control non-preconditioned group. Preconditioning induced by a brief period of 10-min small intestine ischaemia significantly reduced infarct size (6.5±1.9%, P〈0.01 vs. the control non-preconditioned group) and decreased CK release (3092±236 and 1094±117 U/l for myocardial ischaemia-reperfusion and preconditioning plus myocardial ischemia-reperfusion, respectively, P〈0.01), and the protection was partly abolished by pretreatment with capsaicin (50 mg/kg, s.c.) 4 days before the experiments. A brief period of anterior mesenteric artery occlusion caused an increase in the plasma level of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI), an effect which was abolished by pretreatment with capsaicin. Similar protection was shown in the animals subjected to a brief period of anterior mesenteric artery occlusion 24 h before coronary artery occlusion, and this delayed protection was also abolished partly by pretreatment with capsaicin. Capsaicin treatment (50 mg/kg, s.c.) alone also protected the ischa-emic myocardium. The results suggest that brief ischaemia of the small intestine induces both early and delayed protection against reperfusion-induced myocardial injury, and the effects are, at least partly, related to the activation of capsaicin-sensitive sensory nerves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00005348
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A dynamic-mechanical study of polycarbonate-polyester blends (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 40 (1990), S. 1891-1902 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Bisphenol-A polycarbonate and an aromatic linear copolyester were melt blended for dynamic mechanical tests using a Dynastat. Corresponding powders were used in thermal analysis by differential scanning calorimetry. The deduced glass transition temperatures of the pure polymers and blends were compared to estimate the miscibility of the two polymers.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070401108
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A dynamic-mechanical study of polycarbonate-polystyrene blends (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 40 (1990), S. 1881-1890 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Bisphenol-A polycarbonate (PC) and polystyrene (PS) were melt-blended and molded for dynamic mechanical tests on a Dynastat. Corresponding powders were submitted to thermal analysis using the differential scanning calorimeter. The deduced glass transition temperatures of the blends and those of the pure polymers were compared to estimate the miscibility of the two polymers.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070401107
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    Paper (German National Licenses)
    Fulltext
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