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  • 1
    Electronic Resource
    Electronic Resource
    Angioarchitecture associated with haemorrhage in cerebral arteriovenous malformations: a prognostic statistical model (1997)
    Springer
    Neuroradiology 39 (1997), S. 52-58 
    Details
    ISSN: 1432-1920
    Keywords: Key words Arteriovenous malformation ; cerebral ; Haemorrhage ; Cerebral angiography ; Prognostic factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The overall haemorrhagic risk of a cerebral arteriovenous malformation (cAVM) is 2–4 % per year. However, the individual risk of haemorrhage has never been determined. This study was undertaken to assess the haemorrhage risk of an individual cAVM. Neuroangiographic findings of 160 cAVM were analysed retrospectively, looking at 30 angiographic features. A statistical model was established by logistic regression to evaluate the risk of an individual cAVM. We statistically correlated 15 parameters with the haemorrhage risk. The statistical model includes five independent parameters. Four are unfavourable: exclusively deep drainage, venous stenoses, venous reflux and the radio of afferent to efferent systems; one is favourable: venous recruitment. This model quantifies the individual risk of haemorrhage. When this model is applied to the population studied, the error rate is 5 %. This model can contribute to therapeutic strategy, and to a better understanding of the natural history of cAVM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050367
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  • 2
    Electronic Resource
    Electronic Resource
    Serial stereotactic biopsies and CT scan in gliomas: correlative study in 100 astrocytomas, oligo-astrocytomas and oligodendrocytomas (1987)
    Springer
    Journal of neuro-oncology 4 (1987), S. 317-328 
    Details
    ISSN: 1573-7373
    Keywords: stereotactic biopsies ; gliomas ; CT scanning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Histologic features of 100 supra-tentorial astrocytomas, oligodendrogliomas and oligo-astrocytomas obtained from serial stereotactic biopsies were compared with the corresponding CT scans. Topographic comparisons provided by visualization of the biopsy trajectories on post-biopsy CT scans were available in 24 cases. Areas of contrast enhancement and low attenuation were compared with the histologic grade of malignancy, tumor delimitation and structural type. The latter was determined as follows: Type I-solid tumor tissue without significant peripheral isolated tumor cells; Type II-solid tumor tissue associated with peripheral isolated tumor cells; Type III-isolated tumor cells only. There was a strong correlation between areas of contrast enhancement and tumor microvascularity. In addition, contrast enhancement occurred only in the solid tumor tissue component of the neoplasm. This correlation accounted for the relationship observed between CT images and the structural type of glioma. Contrast enhancement was constant in structural type I gliomas, inconstant in structural type II, and absent in structural type III. No correlation was found between malignancy and contrast enhancement. Contrast enhancement occurred in all grades of malignancy but was a constant feature of grade 4 gliomas. The volume of the tumors could not be reliably determined from CT images alone. Areas of low attenuation on contrast CT scans could correspond to either peritumoral edema or to edematous parenchyma infiltrated by isolated tumor cells. Serial stereotactic biopsies combined with calculations based on the CT scan provided a more precise definition of the tumor volume and identification of structural type. Such classification may prove useful in prospective analysis of various modes of therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195602
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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