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  • ^3^2P-postlabelling analysis  (2)
  • Calcite  (1)
  • Diabetes mellitus  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mutation Research Letters 282 (1992), S. 139-145 
    ISSN: 0165-7992
    Keywords: DNA ; Nuclease P1 enhancement ; ^3^2P-Postlabelling assay ; ^3^2P-postlabelling analysis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 292 (1993), S. 113-122 
    ISSN: 0165-1161
    Keywords: Antibody ; DNA ; DNA adducts ; ELISA ; ^3^2P-postlabelling analysis ; anti-Benzo[a]pyrene-diol-epoxide-DNA antibody analysis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 4 (1969), S. 314-329 
    ISSN: 1432-0827
    Keywords: Sponge ; Spicules ; Calcite ; Analysis ; Specific gravity ; Speciation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé Nous donnons les résultats d'analyses chimiques, d'examens aux rayons infra-rouge, et d'examens par diffraction des rayons-X, des spicules de sept espèces des Éponges Calcaires avec aussi les valeurs de gravité spcéifique. Les spicules se composent de calcite et de magnésium. Nous avons découvert des traces de quartz, mais nous les attribuons à la contamination. Nous avons cherché l'aragonite, sans la trouver, bien que la présence du quartz en rende plus difficile la recherche. Le contenu de Mg2+ a varié de 1,25 à 3,15 pour cent d'une espèce à l'autre, s'élevant selon la grandeur des spicules dans les deux espèces que nous avons étudiées. Il était aussi en corrélation étroite avec le déplacement du sommet 112 de diffraction. Des composants présents en quantité moindre, et dont nous avons estimé le pourcentage, se trouvaient être Sr2+, Na+ et SO 4 2− . Sr2+ était relativement invariable, les deux autres étaient variables. Nous avons découvert aussi des traces de Al3+, Si, Mn2+, Ba2+ et Li+. Les valeurs de gravité spécifique s'échelonnaient de 2,58 à 2,62, les spicules plus petits fournissant la plus grande variation. Nous considérons la composition par rapport à la sécrétion de spicules et à la classification de la Calcarea.
    Abstract: Zusammenfassung Die Ergebnisse von chemischen, röntgenographischen und infraroten Analysen, zusammen mit Bestimmungen von spezifischem Gewicht, werden für die Nadeln von 7 species der Kalkschwämme dargestellt. Die Nadeln setzen sich zusammen aus magnesiahaltigem Calcit. Spuren von Quartz wurden nachgewiesen, die sich aber auf Verunreinigungen zurückführen lassen. Aragonit wurde gesucht, aber nicht gefunden, obgleich die Anwesenheit von Quartz seine Feststellung erschwert. Der Mg2+-Inhalt variierte von 1,25–3,15% zwischen den Species, und nahm mit wachsender Nadelgröße bei den beiden untersuchten Species zu; es gibt auch enge Wechselbeziehungen zur Absetzung der Calcit-112-Diffraktionsspitze. Es gibt vermutlich geringere Mengen von Sr2+, Na+, und SO 4 2− . Sr2+ war relative beständig, die anderen zwei veränderlich. Spuren von Al3+, Si, Mn2+, Ba2+ und Li+ wurden auch nachgewiesen. Die durchschnittlichen spezifischen Gewichte veränderten sich von 2,58–2,62, und kleinere Nadeln variieren stärker. Die Zusammensetzung wird mit Hinsicht auf die Ausscheidung der Nadeln und die Klassenordnung der Kalkschwämme betrachtet.
    Notes: Abstract The results of chemical, X-ray diffraction and infra-red analyses, together with specific gravity determinations, are presented for the spicules of seven species of Calcarea. The spicules are composed of magnesian calcite. Traces of quartz were detected, but are ascribed to contamination. Aragonite was sought but not proven, although the presence of quartz complicates its detection. The Mg content varied from 1.25–3.15% between species, and increased with spicule size in the two species studied; it also correlated closely with the displacement of the calcite 112 diffraction peak. Minor constituents estimated were Sr2+, Na+ and SO 4 2− :Sr2+ was relatively constant, the other two variable. Traces of Al3+, Si, Mn2+ and Li+ were also detected. Average specific gravities ranged from 2.58–2.62, smaller spicules having a wider range Composition is considered in relation to spicule secretion and classification of the Calcarea.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0428
    Keywords: Diabetes mellitus ; Indian Asian ; MHC ; tumour necrosis factor ; linkage disequilibrium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tumour necrosis factor gene polymorphism has been proposed as a determinant of Type 1 (insulin-dependent) diabetes mellitus. Tumour necrosis factor-beta gene polymorphisms were analysed in 40 North Indian Asian Type 1 diabetic patients and 63 control subjects. A 5.5 kilobase gene fragment was significantly increased among the patients (82.5% vs 52%, p c〈0.01). A 10.5 kilobase fragment was significantly reduced among the patients (70% vs 90.5%, p c〈0.02). The 5.5 kilobase fragment was associated with DR3, and was not significantly increased among DR3-positive patients compared with DR3-positive control subjects. The 5.5 kilobase/5.5 kilobase genotype was increased among the diabetic subjects (30% vs 9.5%, p c〈0.03). The 10.5 kilobase/10.5 kilobase genotype was reduced among the diabetic subjects (17.5% vs 47.5%, p c〈0.02). The 5.5 kilobase/10.5 kilobase genotype was not significantly associated with disease. These findings contrast with those in a white Caucasian population, suggesting that tumour necrosis factor-beta polymorphisms do not predispose to Type 1 diabetes directly, but are in linkage disequilibrium with disease susceptibility alleles at other MHC loci.
    Type of Medium: Electronic Resource
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