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  • 1
    Electronic Resource
    Electronic Resource
    Postnatal variations in the number and size of C-cells in the rat thyroid gland (1995)
    Springer
    Cell & tissue research 280 (1995), S. 659-663 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Thyroid gland ; C-cells ; Postnatal development ; Calcitonin ; Stereology ; Rat (Wistar)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The heterogeneous distribution of thyroid C-cells has until now hindered an objective evaluation of changes caused by age or experimental stimuli. To overcome this, a rigorous methodology has been designed to detect variations in shape, size, and number of C-cells throughout development. Using this methodology, we have demonstrated that C-cells do not significantly alter their shape with age. However, their volume increases gradually from 472 μm3 in newborn rats to 1653 μm3 in 120-day-old animals. Over the same time period, the mean number of C-cells within the thyroid gland increased 9-fold (from 1.6×104 to 1.5×105), and the number of C-cells per unit area decreased (from 6.15×104/mm3 to 2.6×104/mm3). We conclude that there are marked variations in size, total number, and number of C-cells per unit area in the rat thyroid gland after birth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318368
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Quantitative changes in the frequency and distribution of the C-cell population in the rat thyroid gland with age (1992)
    Springer
    Cell & tissue research 270 (1992), S. 73-77 
    Details
    ISSN: 1432-0878
    Keywords: Thyroid gland ; Calcitonin cells (C-cells) ; Follicular cells ; Immunoperoxidase reaction ; Point-counting method ; Rat (Wistar)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The development of calcitonin cells (C-cells) was investigated in rat thyroid glands from birth to 120 days, using an immunoperoxidase technique and a point-counting method. The proportion of C-cells to follicular cells was 4.5% on the day of birth and increased progressively to 10.4% by 120 days. The highest density of C-cells was noted in the mid-region of the lobes along a longitudinal axis. The caudal and cephalic regions of the lobes contained smaller numbers of C-cells. The C-cells tended to be more numerous in the posterior aspects of the lobes. Although the numbers of C-cells in 120-day-old animals were markedly increased as compared to animals at the time of birth, the cell distributions within the glands were similar at all ages.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00381881
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Postnatal variations in the number and size of C-cells in the rat thyroid gland (1995)
    Springer
    Cell & tissue research 280 (1995), S. 659-663 
    Details
    ISSN: 1432-0878
    Keywords: Thyroid gland ; C-cells ; Postnatal development ; Calcitonin ; Stereology ; Rat (Wistar)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The heterogeneous distribution of thyroid C-cells has until now hindered an objective evaluation of changes caused by age or experimental stimuli. To overcome this, a rigorous methodology has been designed to detect variations in shape, size, and number of C-cells throughout development. Using this methodology, we have demonstrated that C-cells do not significantly alter their shape with age. However, their volume increases gradually from 472 μm3 in newborn rats to 1653 μm3 in 120-day-old animals. Over the same time period, the mean number of C-cells within the thyroid gland increased 9-fold (from 1.6x104 to 1.5x105), and the number of C-cells per unit area decreased (from 6.15x104/mm3 to 2.6x104/mm3). We conclude that there are marked variations in size, total number, and number of C-cells per unit area in the rat thyroid gland after birth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318368
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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