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  • 1
    Electronic Resource
    Electronic Resource
    Linear discriminant analysis of regional ejection fractions in the diagnosis of coronary artery disease (1987)
    Springer
    European journal of nuclear medicine 12 (1987), S. 602-604 
    Details
    ISSN: 1619-7089
    Keywords: Gated blood pool ; Computer processing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the application of linear discriminant analysis to the computer assisted interpretation of rest and exercise gated blood pool studies. Data were obtained in 45 patients in whom the presence or absence of coronary artery disease was determined by coronary angiography. Automated analysis of regional ejection fractions using a linear discriminant function (LDF) was compared to the fully automated calculation of global ejection fraction and to the subjective evaluation of wall motion. A LDF constructed from the data for the first 31 consecutive patients correctly classified 25/31 (81%). The change in global ejection fraction correctly classified 24/31 (77%) and wall motion analysis 25/31 (81%). In a distint group of 14 patients the same LDF correctly classified 12/14 (86%), global ejection fraction 9/14 (64%) and wall motion analysis 10/14 (71%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00284534
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Assessing neuroreceptor occupancy by continuous infusion of carbon-11 labeled radioligands (1996)
    Springer
    European journal of nuclear medicine 23 (1996), S. 141-144 
    Details
    ISSN: 1619-7089
    Keywords: Equilibrium state ; Continuous infusion ; Carbon-11 radioligands ; Dual-probe detector system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In carbon-11 labeled radiotracer studies of neuroreceptors in the brain, a state of practical equilibrium, monitored with a simple dual-probe detector system, was achieved by injection of a bolus of tracer followed by a continuous infusion of the tracer. After investigating several different bolus-to-infusion activity ratios, we observed that a practical equilibrium state could be achieved with a slope of 0.02±0.001 cpsxkg/µCi/min for [11C]carfentanil studies in normal human beings. The usefulness of this approach to assess neuroreceptor occupancy was demonstrated in two cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01731836
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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