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  • 1
    ISSN: 1432-1238
    Keywords: Key words Inhaled NO ; Cardiac critical care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate whether a trial of inhaled nitric oxide (NO) differentiates reversible pulmonary vasoconstriction from fixed anatomic obstruction to pulmonary blood flow after surgery for congenital heart disease in patients at risk for pulmonary hypertension.¶Design: Prospective cohort study.¶Setting: Tertiary care children's hospital.¶Patients: 15 neonate and infants with elevated pulmonary artery or right ventricular pressure or with clinical signs suggestive of high pulmonary vascular resistance in the early postoperative period following repair of congenital heart disease.¶Intervention: 30-min trial of 40 ppm inhaled NO.¶Results: 5 patients responded to inhaled NO, 2 patients were weaned from extracorporeal support with NO. Four were maintained on continuous inhaled NO for 3 to 5 days. All the responders survived. Ten patients did not respond to NO. An important anatomic obstruction was found with echocardiography or angiography in all 10 patients. Reintervention was performed in 6/10 (4 stent placement, 1 balloon angioplasty of pulmonary arteries and 1 revision of systemic to pulmonary shunt). Six of the nonresponders died.¶Conclusion: A trial of inhaled NO after cardiac surgery in neonates and infants may be useful to differentiate reversible pulmonary vasoconstriction from fixed anatomic obstruction and may provide useful information if temporary support with extracorporeal membrane oxygenation is considered. Failure to respond to inhaled NO should prompt further investigations to rule out a residual obstruction.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 237 (1988), S. 258-263 
    ISSN: 1433-8491
    Keywords: Right-posterior slow waves in EEG ; Schizophrenia ; Maturational deficit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intermittent right-posterior accentuated slow waves (irregular theta and/or delta waves: IRP phenomenon) in the EEG showed an incidence of about 5% in the total in-patients of a psychiatric university hospital. The IRP phenomenon was found in 7.5% of patients with schizophrenic psychoses, 2% of patients with affective psychoses and in 2.4% of patients with neurotic and personality disorders. The IRP groups differed from control groups in a number of sociobiographical and clinical characteristics. Having repeatedly confirmed these relationships with different samples, we regard IRP patients, irrespective of the diagnosis given, as having a maturational deficit of brain function.
    Type of Medium: Electronic Resource
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