Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 366 (1976), S. 153-157 
    ISSN: 1432-2013
    Schlagwort(e): Blood flow ; Cardiac output distribution ; Cold stress ; Microspheres ; Thermoregulation ; Sheep circulation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Conscious adult Merino sheep were studied in a thermoneutral environment and then during cold exposure. Microspheres labelled with141Ce,51Cr,85Sr, and46Sc were used to measure blood flow ( $$\dot Q$$ ) in most tissues of the body. (Microspheres labelled with125I were found to be unsatisfactory.) Cold exposure which caused a marked decrease in skin surface temperature and mild, continuous shivering but no change in deep body temperature, was associated with mean increases in oxygen consumption, heart rate, and cardiac output (C.O.) of 100%, 62%, and 48%, respectively; blood pressure and total peripheral resistance were unchanged. There was approximately a 6-fold increase in $$\dot Q$$ in perirenal white adipose tissue, and a 3- to 4-fold increase in muscles of the upper foreleg and hindleg, and the intercostals; myocardial $$\dot Q$$ also increased significantly. There was a marked decrease in $$\dot Q$$ in skin of the legs and ears, in the maxillo turbinals and in the nasal mucosa, and a decrease in the total proportion of C.O. passing through arteriovenous anastomoses. Thus, not only did C.O. increase, but there was a redistribution appropriate to meet the challenge with which the animal was confronted.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    ISSN: 1432-2013
    Schlagwort(e): Arteriovenous Anastomoses ; Cutaneous Blood Flow ; Thermoregulation ; Microspheres
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Radioactive microsphere measurements of blood flow in the hindlimb of the conscious sheep indicate that CNS temperatures have a potent influence on blood flow through cutaneous AVA's but not capillaries, and vice versa for superficial body temperatures.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 372 (1977), S. 157-164 
    ISSN: 1432-2013
    Schlagwort(e): Blood flow ; Cardiac output distribution ; Hypothalamic control of blood flow ; Thermoregulation ; Microspheres
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Radioactive microspheres were used to assess the influence of hypothalamic temperature on tissue blood flow and the regional distribution of cardiac output in conscious sheep chronically prepared with hypothalamic thermodes. Hypothalamic heating elicited panting in 6 animals, and in these, blood flow rate increased in respiratory muscles and decreased in the thyroids, kidneys, spleen and gut; cardiac output did not change, but was redistributed in a pattern similar to that seen during spinal cord heating, which differs from that which occurs during exposure to a warm environment. Four other animals did not pant in response to hypothalamic heating, but showed small but definite increases in capillary blood flow in skin of extremities. Reasons for the two different types of response to heating are discussed. The failure to detect increases in microsphere-measured extremity skin blood flow in the first group and only small changes in the second group above, despite the increased skin temperature always seen with hypothalamic heating, is attributed to specific influences of CNS stimulation on arteriovenous anastomoses. In 6 animals, hypothalamic cooling elicited visible shivering associated with increased oxygen consumption; blood flow rate decreased in skin and increased in respiratory and non-respiratory muscles, fat and the myocardium; cardiac output showed an increase and a redistribution similar to that which occurs during exposure to a cold environment. Arterial blood pressure was steady, but there were changes in regional vascular resistance. Therefore, and in view of other studies, the blood flow responses observed are attributed to regional differentiation of sympathetic activity.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    ISSN: 1432-2013
    Schlagwort(e): Skin blood flow ; Arteriovenous anastomoses ; Microspheres
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Using radioactive plastic microspheres in conscious sheep, cardiac output is measured by dose injection into a vein, and sampling from the pulmonary artery. Partition of organ blood flow between capillaries and arteriovenous anastomoses is derived from cardiac output and the radioactivity in pulmonary artery blood sampled after dose injection into the artery supplying the organ. Validation tests are presented. The hindlimb is shown to be a suitable model for studying thermal influences on skin blood flow. In contrast to other techniques or previous applications of microspheres: (a) conscious, chronically prepared animals are used, (b) there is no need to kill the animal to obtain results, (c) only small doses are necessary, (d) the one nuclide label can be used repeatedly, and (e) there is no need for precisely matched doses.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    ISSN: 1432-2013
    Schlagwort(e): Skin blood flow ; Arteriovenous anastomoses ; Thermoregulation ; Heat stress ; Cold stress ; Microspheres
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Using radioactive microsphere and electromagnetic techniques, hindleg vascular responses were studied in 38 conscious, chronically prepared sheep subjected to either exposure to a warm environment, and/or local warming of the hypothalamus, spinal cord, forelegs or hindlegs. The total proportion of cardiac output passing through AVA's was increased by all treatments. AVA flow in hindleg skin was increased but capillary flow was unchanged by warming the hypothalamus, spinal cord or forelegs. AVA flow was unchanged but capillary flow was increased by warming the ambient air or the hindlegs alone. Equivalent cooling treatments resulted in AVA and capillary flow changes converse to warming. It is concluded that, in sheep, blood flow through cutaneous AVA's is controlled by specific thermoregulatory reflexes, whereas capillary flow is the target of local temperature effects. A significant role for the direction of the thermal gradient across the skin is implicated.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...